Primary Tracheobronchial Amyloidosis Presenting with an Upper Airway Obstruction

Zekewos Demissie,1 Nahom Zemedkun,1 Abraham Demile,1 Berhanu Nega,2 Yonas Bekuretsion,3 Bisrat Getachew,4 Bethelhem Berhanu5 1Department of Internal Medicine, Lancet General Hospital, Addis Ababa, Ethiopia; 2Department of Surgery, Division of Cardiothoracic Surgery, College of Health Sciences, Addis...

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Main Authors: Demissie Z, Zemedkun N, Demile A, Nega B, Bekuretsion Y, Getachew B, Berhanu B
Format: Article
Language:English
Published: Dove Medical Press 2023-11-01
Series:International Medical Case Reports Journal
Subjects:
Online Access:https://www.dovepress.com/primary-tracheobronchial-amyloidosis-presenting-with-an-upper-airway-o-peer-reviewed-fulltext-article-IMCRJ
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author Demissie Z
Zemedkun N
Demile A
Nega B
Bekuretsion Y
Getachew B
Berhanu B
author_facet Demissie Z
Zemedkun N
Demile A
Nega B
Bekuretsion Y
Getachew B
Berhanu B
author_sort Demissie Z
collection DOAJ
description Zekewos Demissie,1 Nahom Zemedkun,1 Abraham Demile,1 Berhanu Nega,2 Yonas Bekuretsion,3 Bisrat Getachew,4 Bethelhem Berhanu5 1Department of Internal Medicine, Lancet General Hospital, Addis Ababa, Ethiopia; 2Department of Surgery, Division of Cardiothoracic Surgery, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; 3Department of Pathology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; 4Department of Otolaryngology, Head and Neck Surgery, St. Paul Millennium Medical College, Addis Ababa, Ethiopia; 5Department of Radiology, St. Paul Millennium Medical College, Addis Ababa, EthiopiaCorrespondence: Zekewos Demissie, Email zakdem61@gmail.comAbstract: This is a case of localized primary tracheobronchial amyloidosis in a patient who presented with upper airway obstruction. Tracheobronchial amyloidosis is a type of localized bronchopulmonary amyloidosis that is frequently overlooked. It involves the deposition of amyloid protein on the tracheal and bronchial tissue, leading to progressive tracheal stenosis and airway obstruction that can be seen on imaging as a tracheal mass. Because of its significant diagnostic difficulty and therapeutic conundrum, it ought to be considered in the differential diagnosis of upper airway symptoms with an unknown etiology.Keywords: tracheobronchial amyloidosis, tracheal mass, upper airway obstruction
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spelling doaj.art-3483c8ff2e934c2d8379c2066c962cbb2023-11-19T18:03:58ZengDove Medical PressInternational Medical Case Reports Journal1179-142X2023-11-01Volume 1675776188278Primary Tracheobronchial Amyloidosis Presenting with an Upper Airway ObstructionDemissie ZZemedkun NDemile ANega BBekuretsion YGetachew BBerhanu BZekewos Demissie,1 Nahom Zemedkun,1 Abraham Demile,1 Berhanu Nega,2 Yonas Bekuretsion,3 Bisrat Getachew,4 Bethelhem Berhanu5 1Department of Internal Medicine, Lancet General Hospital, Addis Ababa, Ethiopia; 2Department of Surgery, Division of Cardiothoracic Surgery, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; 3Department of Pathology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; 4Department of Otolaryngology, Head and Neck Surgery, St. Paul Millennium Medical College, Addis Ababa, Ethiopia; 5Department of Radiology, St. Paul Millennium Medical College, Addis Ababa, EthiopiaCorrespondence: Zekewos Demissie, Email zakdem61@gmail.comAbstract: This is a case of localized primary tracheobronchial amyloidosis in a patient who presented with upper airway obstruction. Tracheobronchial amyloidosis is a type of localized bronchopulmonary amyloidosis that is frequently overlooked. It involves the deposition of amyloid protein on the tracheal and bronchial tissue, leading to progressive tracheal stenosis and airway obstruction that can be seen on imaging as a tracheal mass. Because of its significant diagnostic difficulty and therapeutic conundrum, it ought to be considered in the differential diagnosis of upper airway symptoms with an unknown etiology.Keywords: tracheobronchial amyloidosis, tracheal mass, upper airway obstructionhttps://www.dovepress.com/primary-tracheobronchial-amyloidosis-presenting-with-an-upper-airway-o-peer-reviewed-fulltext-article-IMCRJtracheobronchial amyloidosistracheal massupper airway obstruction
spellingShingle Demissie Z
Zemedkun N
Demile A
Nega B
Bekuretsion Y
Getachew B
Berhanu B
Primary Tracheobronchial Amyloidosis Presenting with an Upper Airway Obstruction
International Medical Case Reports Journal
tracheobronchial amyloidosis
tracheal mass
upper airway obstruction
title Primary Tracheobronchial Amyloidosis Presenting with an Upper Airway Obstruction
title_full Primary Tracheobronchial Amyloidosis Presenting with an Upper Airway Obstruction
title_fullStr Primary Tracheobronchial Amyloidosis Presenting with an Upper Airway Obstruction
title_full_unstemmed Primary Tracheobronchial Amyloidosis Presenting with an Upper Airway Obstruction
title_short Primary Tracheobronchial Amyloidosis Presenting with an Upper Airway Obstruction
title_sort primary tracheobronchial amyloidosis presenting with an upper airway obstruction
topic tracheobronchial amyloidosis
tracheal mass
upper airway obstruction
url https://www.dovepress.com/primary-tracheobronchial-amyloidosis-presenting-with-an-upper-airway-o-peer-reviewed-fulltext-article-IMCRJ
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