Regulation of Human Natural Killer Cell IFN-γ Production by MicroRNA-146a via Targeting the NF-κB Signaling Pathway

Regulation of Human Natural Killer Cell IFN-γ Production by MicroRNA-146a via Targeting the NF-κB Signaling Pathway

Natural killer (NK) cells are one group of innate lymphocytes that are important for host defense against malignancy and viruses. MicroRNAs (miRNAs) play a critical role in regulating responses of immune cells including NK cells. Accumulating evidence suggests that miR-146a is involved in the regula...

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Bibliographic Details
Main Authors: Hongwei Wang, Yibo Zhang, Xiaojin Wu, Yufeng Wang, Hanwei Cui, Xinxin Li, Jianying Zhang, Norman Tun, Yong Peng, Jianhua Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Immunology
Subjects:
natural killer cells
microRNA
IFN-γ
miR-146a
IRAK1
TRAF6
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00293/full

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