Genome-Wide fitness analysis of group B Streptococcus in human amniotic fluid reveals a transcription factor that controls multiple virulence traits.

Genome-Wide fitness analysis of group B Streptococcus in human amniotic fluid reveals a transcription factor that controls multiple virulence traits.

Streptococcus agalactiae (group B Streptococcus; GBS) remains a dominant cause of serious neonatal infections. One aspect of GBS that renders it particularly virulent during the perinatal period is its ability to invade the chorioamniotic membranes and persist in amniotic fluid, which is nutritional...

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Bibliographic Details
Main Authors: Allison N Dammann, Anna B Chamby, Andrew J Catomeris, Kyle M Davidson, Hervé Tettelin, Jan-Peter van Pijkeren, Kathyayini P Gopalakrishna, Mary F Keith, Jordan L Elder, Adam J Ratner, Thomas A Hooven
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009116

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