Psychotropic drug use among children and adolescents in the Nordic countries - A systematic literature review

Introduction The Nordic countries have similar health care and welfare systems, and rather homogenous populations. Therefore, it is reasonable to expect similar use of psychotropic drugs. However, recent studies show marked differences in a range of psychotropic drug classes among children and adol...

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Main Authors: D. Ollerup, S. Elkrog, M. Stoltz-Andersen, H. Stubmark, L. Rasmussen, R. Wesselhoeft
Format: Article
Language:English
Published: Cambridge University Press 2022-06-01
Series:European Psychiatry
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S092493382201080X/type/journal_article
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author D. Ollerup
S. Elkrog
M. Stoltz-Andersen
H. Stubmark
L. Rasmussen
R. Wesselhoeft
author_facet D. Ollerup
S. Elkrog
M. Stoltz-Andersen
H. Stubmark
L. Rasmussen
R. Wesselhoeft
author_sort D. Ollerup
collection DOAJ
description Introduction The Nordic countries have similar health care and welfare systems, and rather homogenous populations. Therefore, it is reasonable to expect similar use of psychotropic drugs. However, recent studies show marked differences in a range of psychotropic drug classes among children and adolescents in Sweden, Norway, and Denmark. Objectives To review the literature regarding psychotropic drug use among children and adolescents in the Nordic countries. Methods We performed a critical systematic literature review according to PRISMA guidelines and registered the study protocol at PROSPERO. Three scientific databases were used: PsycINFO, EMBASE and PubMed. Inclusion criteria were: 1) Age: 3-19 years, 2) Country: Denmark, including Faroe Islands and Greenland, Sweden, Norway, Finland, including Aland, and Iceland, 3) Drug of interest: Psychotropics, including Antidepressants, ADHD medication, antipsychotics, hypnotics, anxiolytics, 4) Population based study sample, 5) Observational study design, 6) Original data, 7) English language, 8) Publication date: 2010-2021. The review process was performed by four reviewers in three steps: 1) title/abstract screening, 2) full text screening, and 3) data extraction, including risk of bias assessment. Before study initiation, acceptable interrater reliability was ensured by pilot tests. Results The literature search was conducted October 6th, 2021. The PsycINFO database gave 285 hits, EMBASE 1190 hits and PubMed 2185 hits. In total, the literature search gave 3660 hits, of which 294 were duplicates, leaving us with 3366 references. The first screening phase is in process and results will be presented at the EPA conference. Conclusions The results of the systematic review will be interpreted and discussed. Disclosure No significant relationships.
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spelling doaj.art-3496280945894a0691ab5fdbc5bc0f422023-11-17T05:08:08ZengCambridge University PressEuropean Psychiatry0924-93381778-35852022-06-0165S425S42610.1192/j.eurpsy.2022.1080Psychotropic drug use among children and adolescents in the Nordic countries - A systematic literature reviewD. Ollerup0S. Elkrog1M. Stoltz-Andersen2H. Stubmark3L. Rasmussen4R. Wesselhoeft5University of Southern Denmark, Clinical Pharmacology, Pharmacy And Environmental Medicine, Department Of Public Health, Odense, DenmarkUniversity of Southern Denmark, Clinical Pharmacology, Pharmacy And Environmental Medicine, Department Of Public Health, Odense, DenmarkUniversity of Southern Denmark, Clinical Pharmacology, Pharmacy And Environmental Medicine, Department Of Public Health, Odense, DenmarkUniversity of Southern Denmark, Clinical Pharmacology, Pharmacy And Environmental Medicine, Department Of Public Health, Odense, DenmarkUniversity of Southern Denmark, Clinical Pharmacology, Pharmacy And Environmental Medicine, Department Of Public Health, Odense, DenmarkUniversity of Southern Denmark, Clinical Pharmacology, Pharmacy And Environmental Medicine, Department Of Public Health, Odense, Denmark Introduction The Nordic countries have similar health care and welfare systems, and rather homogenous populations. Therefore, it is reasonable to expect similar use of psychotropic drugs. However, recent studies show marked differences in a range of psychotropic drug classes among children and adolescents in Sweden, Norway, and Denmark. Objectives To review the literature regarding psychotropic drug use among children and adolescents in the Nordic countries. Methods We performed a critical systematic literature review according to PRISMA guidelines and registered the study protocol at PROSPERO. Three scientific databases were used: PsycINFO, EMBASE and PubMed. Inclusion criteria were: 1) Age: 3-19 years, 2) Country: Denmark, including Faroe Islands and Greenland, Sweden, Norway, Finland, including Aland, and Iceland, 3) Drug of interest: Psychotropics, including Antidepressants, ADHD medication, antipsychotics, hypnotics, anxiolytics, 4) Population based study sample, 5) Observational study design, 6) Original data, 7) English language, 8) Publication date: 2010-2021. The review process was performed by four reviewers in three steps: 1) title/abstract screening, 2) full text screening, and 3) data extraction, including risk of bias assessment. Before study initiation, acceptable interrater reliability was ensured by pilot tests. Results The literature search was conducted October 6th, 2021. The PsycINFO database gave 285 hits, EMBASE 1190 hits and PubMed 2185 hits. In total, the literature search gave 3660 hits, of which 294 were duplicates, leaving us with 3366 references. The first screening phase is in process and results will be presented at the EPA conference. Conclusions The results of the systematic review will be interpreted and discussed. Disclosure No significant relationships. https://www.cambridge.org/core/product/identifier/S092493382201080X/type/journal_articleNordic countriessystematic reviewchildren and adolescentspsychotropics drug use
spellingShingle D. Ollerup
S. Elkrog
M. Stoltz-Andersen
H. Stubmark
L. Rasmussen
R. Wesselhoeft
Psychotropic drug use among children and adolescents in the Nordic countries - A systematic literature review
European Psychiatry
Nordic countries
systematic review
children and adolescents
psychotropics drug use
title Psychotropic drug use among children and adolescents in the Nordic countries - A systematic literature review
title_full Psychotropic drug use among children and adolescents in the Nordic countries - A systematic literature review
title_fullStr Psychotropic drug use among children and adolescents in the Nordic countries - A systematic literature review
title_full_unstemmed Psychotropic drug use among children and adolescents in the Nordic countries - A systematic literature review
title_short Psychotropic drug use among children and adolescents in the Nordic countries - A systematic literature review
title_sort psychotropic drug use among children and adolescents in the nordic countries a systematic literature review
topic Nordic countries
systematic review
children and adolescents
psychotropics drug use
url https://www.cambridge.org/core/product/identifier/S092493382201080X/type/journal_article
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