Unraveling a Force-Generating Allosteric Pathway of Actomyosin Communication Associated with ADP and P<sub>i</sub> Release

Unraveling a Force-Generating Allosteric Pathway of Actomyosin Communication Associated with ADP and P<sub>i</sub> Release

The actomyosin system generates mechanical work with the execution of the power stroke, an ATP-driven, two-step rotational swing of the myosin-neck that occurs post ATP hydrolysis during the transition from weakly to strongly actin-bound myosin states concomitant with P<sub>i</sub> relea...

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Bibliographic Details
Main Authors: Peter Franz, Wiebke Ewert, Matthias Preller, Georgios Tsiavaliaris
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
myosin
actin
ATPase cycle
transient kinetics
duty ratio
allosteric communication
Online Access:https://www.mdpi.com/1422-0067/22/1/104

Internet

https://www.mdpi.com/1422-0067/22/1/104

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