Brain docosahexaenoic acid [DHA] incorporation and blood flow are increased in chronic alcoholics: a positron emission tomography study corrected for cerebral atrophy.

Brain docosahexaenoic acid [DHA] incorporation and blood flow are increased in chronic alcoholics: a positron emission tomography study corrected for cerebral atrophy.

Chronic alcohol dependence has been associated with disturbed behavior, cerebral atrophy and a low plasma concentration of docosahexaenoic acid (DHA, 22∶6n-3), particularly if liver disease is present. In animal models, excessive alcohol consumption is reported to reduce brain DHA concentration, sug...

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Bibliographic Details
Main Authors: John C Umhau, Weiyin Zhou, Shantalaxmi Thada, James Demar, Nahed Hussein, Abesh K Bhattacharjee, Kaizong Ma, Sharon Majchrzak-Hong, Peter Herscovitch, Norman Salem, Abigail Urish, Joseph R Hibbeln, Stephen C Cunnane, Stanley I Rapoport, Jussi Hirvonen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3788756?pdf=render

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