QSAR, molecular docking and ADMET properties in silico studies of novel 4,5,6,7-tetrahydrobenzo[D]-thiazol-2-Yl derivatives derived from dimedone as potent anti-tumor agents through inhibition of C-Met receptor tyrosine kinase
A quantitative structure-activity relationship (QSAR) study is performed on 48 novel 4,5,6,7-tetrahydrobenzo[D]-thiazol-2 derivatives as anticancer agents capable of inhibiting c-Met receptor tyrosine kinase. The present study is conducted using multiple linear regression, multiple nonlinear regress...
Príomhchruthaitheoirí: | , , , , , |
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Formáid: | Alt |
Teanga: | English |
Foilsithe / Cruthaithe: |
Elsevier
2021-07-01
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Sraith: | Heliyon |
Ábhair: | |
Rochtain ar líne: | http://www.sciencedirect.com/science/article/pii/S2405844021015668 |