Geraniol prevents CCl4-induced hepatotoxicity via suppression of hepatic oxidative stress, pro-inflammation and apoptosis in rats

Geraniol prevents CCl4-induced hepatotoxicity via suppression of hepatic oxidative stress, pro-inflammation and apoptosis in rats

Carbon tetrachloride (CCl4) is a classic chemical hepatotoxicant that triggers liver damage through hepatic exacerbation of oxidative stress. Geraniol (GRL) is a natural bioactive acyclic monoterpene with several pharmacological effects. We thus explored whether GRL could prevent CCl4-triggered hepa...

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Bibliographic Details
Main Authors: Abdulmohsen I. Algefare, Manal Alfwuaires, Ademola C. Famurewa, Hany Elsawy, Azza Sedky
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Toxicology Reports
Subjects:
Geraniol
Oxidative stress
Hepatotoxicant
Apoptosis
Hepatotoxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750024000076

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