Effect of Selected Factors on the Serum 25(OH)D Concentration in Women Treated for Breast Cancer
Maintaining an optimal vitamin D concentration reduces the risk of recurrence and extends survival time in patients after breast cancer treatment. Data on vitamin D deficiency among Polish women after breast cancer therapy are limited. Thus, the aim of the study was the analysis of vitamin D status...
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MDPI AG
2021-02-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/13/2/564 |
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| author | Agnieszka Radom Andrzej Wędrychowicz Stanisław Pieczarkowski Szymon Skoczeń Przemysław Tomasik |
| author_facet | Agnieszka Radom Andrzej Wędrychowicz Stanisław Pieczarkowski Szymon Skoczeń Przemysław Tomasik |
| author_sort | Agnieszka Radom |
| collection | DOAJ |
| description | Maintaining an optimal vitamin D concentration reduces the risk of recurrence and extends survival time in patients after breast cancer treatment. Data on vitamin D deficiency among Polish women after breast cancer therapy are limited. Thus, the aim of the study was the analysis of vitamin D status in post-mastectomy patients, considering such factors as seasons, social habits, vitamin D supplementation and its measurements. The study involved 94 women after breast cancer treatment. Serum vitamin D concentration was measured, and a questionnaire, gathering demographic and clinical data regarding cancer, diet, exposure to sun radiation, and knowledge of recommendations on vitamin D supplementation, was delivered twice, in both winter and in summer. The control group consisted of 94 age-matched women with no oncological history. In women after breast cancer treatment, 25-hydroxyvitamin D (25(OH)D) deficiency was much more frequent than in the general population. Only about half of the patients supplemented vitamin D at the beginning of the study. After the first test and the issuing of recommendations on vitamin D supplementation, the percentage of vitamin D supplemented patients increased by about 30% in study groups. The average dose of supplement also increased. None of the women that were not supplementing vitamin D and were tested again in winter had optimal 25(OH)D concentration. It was concluded that vitamin deficiency is common in women treated for breast cancer. Medical advising about vitamin D supplementation and monitoring of 25(OH)D concentration should be improved. |
| first_indexed | 2024-03-09T05:03:19Z |
| format | Article |
| id | doaj.art-34a5f5cd4f694f0fa4baf33ba7e0d98d |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-09T05:03:19Z |
| publishDate | 2021-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-34a5f5cd4f694f0fa4baf33ba7e0d98d2023-12-03T12:57:32ZengMDPI AGNutrients2072-66432021-02-0113256410.3390/nu13020564Effect of Selected Factors on the Serum 25(OH)D Concentration in Women Treated for Breast CancerAgnieszka Radom0Andrzej Wędrychowicz1Stanisław Pieczarkowski2Szymon Skoczeń3Przemysław Tomasik4Medical Laboratory Diagmed, Lwowska 20, 33-300 Nowy Sącz, PolandDepartment of Pediatrics, Gastroenterology and Nutrition, Faculty of Medicine, Jagiellonian University Medical College, Wielicka 265, 30-663 Kraków, PolandDepartment of Pediatrics, Gastroenterology and Nutrition, Faculty of Medicine, Jagiellonian University Medical College, Wielicka 265, 30-663 Kraków, PolandDepartment of Oncology and Hematology, Pediatric Institute, Faculty of Medicine, Jagiellonian University Medical College, Wielicka 265, 30-663 Kraków, PolandDepartment of Clinical Biochemistry, Pediatric Institute, Faculty of Medicine, Jagiellonian University Medical College, Wielicka 265, 30-663 Kraków, PolandMaintaining an optimal vitamin D concentration reduces the risk of recurrence and extends survival time in patients after breast cancer treatment. Data on vitamin D deficiency among Polish women after breast cancer therapy are limited. Thus, the aim of the study was the analysis of vitamin D status in post-mastectomy patients, considering such factors as seasons, social habits, vitamin D supplementation and its measurements. The study involved 94 women after breast cancer treatment. Serum vitamin D concentration was measured, and a questionnaire, gathering demographic and clinical data regarding cancer, diet, exposure to sun radiation, and knowledge of recommendations on vitamin D supplementation, was delivered twice, in both winter and in summer. The control group consisted of 94 age-matched women with no oncological history. In women after breast cancer treatment, 25-hydroxyvitamin D (25(OH)D) deficiency was much more frequent than in the general population. Only about half of the patients supplemented vitamin D at the beginning of the study. After the first test and the issuing of recommendations on vitamin D supplementation, the percentage of vitamin D supplemented patients increased by about 30% in study groups. The average dose of supplement also increased. None of the women that were not supplementing vitamin D and were tested again in winter had optimal 25(OH)D concentration. It was concluded that vitamin deficiency is common in women treated for breast cancer. Medical advising about vitamin D supplementation and monitoring of 25(OH)D concentration should be improved.https://www.mdpi.com/2072-6643/13/2/564vitamin D deficiencyvitamin D measurementvitamin D supplementationbreast cancer |
| spellingShingle | Agnieszka Radom Andrzej Wędrychowicz Stanisław Pieczarkowski Szymon Skoczeń Przemysław Tomasik Effect of Selected Factors on the Serum 25(OH)D Concentration in Women Treated for Breast Cancer Nutrients vitamin D deficiency vitamin D measurement vitamin D supplementation breast cancer |
| title | Effect of Selected Factors on the Serum 25(OH)D Concentration in Women Treated for Breast Cancer |
| title_full | Effect of Selected Factors on the Serum 25(OH)D Concentration in Women Treated for Breast Cancer |
| title_fullStr | Effect of Selected Factors on the Serum 25(OH)D Concentration in Women Treated for Breast Cancer |
| title_full_unstemmed | Effect of Selected Factors on the Serum 25(OH)D Concentration in Women Treated for Breast Cancer |
| title_short | Effect of Selected Factors on the Serum 25(OH)D Concentration in Women Treated for Breast Cancer |
| title_sort | effect of selected factors on the serum 25 oh d concentration in women treated for breast cancer |
| topic | vitamin D deficiency vitamin D measurement vitamin D supplementation breast cancer |
| url | https://www.mdpi.com/2072-6643/13/2/564 |
| work_keys_str_mv | AT agnieszkaradom effectofselectedfactorsontheserum25ohdconcentrationinwomentreatedforbreastcancer AT andrzejwedrychowicz effectofselectedfactorsontheserum25ohdconcentrationinwomentreatedforbreastcancer AT stanisławpieczarkowski effectofselectedfactorsontheserum25ohdconcentrationinwomentreatedforbreastcancer AT szymonskoczen effectofselectedfactorsontheserum25ohdconcentrationinwomentreatedforbreastcancer AT przemysławtomasik effectofselectedfactorsontheserum25ohdconcentrationinwomentreatedforbreastcancer |