Effects of Different Dietary Zinc (Zn) Sources on Growth Performance, Zn Metabolism, and Intestinal Health of Grass Carp
This research was conducted to investigate the effects of four dietary zinc (Zn) sources on growth performance, Zn metabolism, antioxidant capacity, endoplasmic reticulum (ER) stress, and tight junctions in the intestine of grass carp <i>Ctenopharyngodon idella</i>. Four Zn sources consi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Antioxidants |
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| Online Access: | https://www.mdpi.com/2076-3921/12/9/1664 |
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| author | Yi-Chuang Xu Hua Zheng Jia-Cheng Guo Xiao-Ying Tan Tao Zhao Yu-Feng Song Xiao-Lei Wei Zhi Luo |
| author_facet | Yi-Chuang Xu Hua Zheng Jia-Cheng Guo Xiao-Ying Tan Tao Zhao Yu-Feng Song Xiao-Lei Wei Zhi Luo |
| author_sort | Yi-Chuang Xu |
| collection | DOAJ |
| description | This research was conducted to investigate the effects of four dietary zinc (Zn) sources on growth performance, Zn metabolism, antioxidant capacity, endoplasmic reticulum (ER) stress, and tight junctions in the intestine of grass carp <i>Ctenopharyngodon idella</i>. Four Zn sources consisted of Zn dioxide nanoparticles (ZnO NPs), Zn sulfate heptahydrate (ZnSO<sub>4</sub>·7H<sub>2</sub>O), Zn lactate (Zn-Lac), and Zn glycine chelate (Zn-Gly), respectively. Grass carp with an initial body weight of 3.54 g/fish were fed one of four experimental diets for 8 weeks. Compared to inorganic Zn (ZnSO<sub>4</sub>·7H<sub>2</sub>O), grass carp fed the ZnO NPs and Zn-Gly diets exhibited better growth performance. Furthermore, grass carp fed the organic Zn (Zn-Lac and Zn-Gly) diets displayed enhanced Zn transport activity, improved intestinal histology, and increased intestinal tight junction-related genes expression compared to other groups. In comparison to other Zn sources, dietary ZnO NPs caused increased Zn deposition and damaged antioxidation capacity by suppressing antioxidant enzymatic activities and related gene expression in the intestine. Grass cap fed the ZnO NPs diet also exhibited lower mRNA abundance of endoplasmic reticulum (ER) stress- and tight junction-associated genes. According to the above findings, it can be concluded that dietary organic Zn addition (Zn-Lac and Zn-Gly) is more beneficial for intestinal health in grass carp compared to inorganic and nanoform Zn sources. These findings provide valuable insights into the application of organic Zn sources, specifically Zn-Lac and Zn-Gly, in the diets for grass carp and potentially for other fish species. |
| first_indexed | 2024-03-10T23:06:13Z |
| format | Article |
| id | doaj.art-34aa05146cd74bdcb5bcea184c76d6bc |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-10T23:06:13Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-34aa05146cd74bdcb5bcea184c76d6bc2023-11-19T09:18:42ZengMDPI AGAntioxidants2076-39212023-08-01129166410.3390/antiox12091664Effects of Different Dietary Zinc (Zn) Sources on Growth Performance, Zn Metabolism, and Intestinal Health of Grass CarpYi-Chuang Xu0Hua Zheng1Jia-Cheng Guo2Xiao-Ying Tan3Tao Zhao4Yu-Feng Song5Xiao-Lei Wei6Zhi Luo7Hubei Hongshan Laboratory, Fishery College, Huazhong Agricultural University, Wuhan 430070, ChinaHubei Hongshan Laboratory, Fishery College, Huazhong Agricultural University, Wuhan 430070, ChinaHubei Hongshan Laboratory, Fishery College, Huazhong Agricultural University, Wuhan 430070, ChinaHubei Hongshan Laboratory, Fishery College, Huazhong Agricultural University, Wuhan 430070, ChinaHubei Hongshan Laboratory, Fishery College, Huazhong Agricultural University, Wuhan 430070, ChinaHubei Hongshan Laboratory, Fishery College, Huazhong Agricultural University, Wuhan 430070, ChinaHubei Hongshan Laboratory, Fishery College, Huazhong Agricultural University, Wuhan 430070, ChinaHubei Hongshan Laboratory, Fishery College, Huazhong Agricultural University, Wuhan 430070, ChinaThis research was conducted to investigate the effects of four dietary zinc (Zn) sources on growth performance, Zn metabolism, antioxidant capacity, endoplasmic reticulum (ER) stress, and tight junctions in the intestine of grass carp <i>Ctenopharyngodon idella</i>. Four Zn sources consisted of Zn dioxide nanoparticles (ZnO NPs), Zn sulfate heptahydrate (ZnSO<sub>4</sub>·7H<sub>2</sub>O), Zn lactate (Zn-Lac), and Zn glycine chelate (Zn-Gly), respectively. Grass carp with an initial body weight of 3.54 g/fish were fed one of four experimental diets for 8 weeks. Compared to inorganic Zn (ZnSO<sub>4</sub>·7H<sub>2</sub>O), grass carp fed the ZnO NPs and Zn-Gly diets exhibited better growth performance. Furthermore, grass carp fed the organic Zn (Zn-Lac and Zn-Gly) diets displayed enhanced Zn transport activity, improved intestinal histology, and increased intestinal tight junction-related genes expression compared to other groups. In comparison to other Zn sources, dietary ZnO NPs caused increased Zn deposition and damaged antioxidation capacity by suppressing antioxidant enzymatic activities and related gene expression in the intestine. Grass cap fed the ZnO NPs diet also exhibited lower mRNA abundance of endoplasmic reticulum (ER) stress- and tight junction-associated genes. According to the above findings, it can be concluded that dietary organic Zn addition (Zn-Lac and Zn-Gly) is more beneficial for intestinal health in grass carp compared to inorganic and nanoform Zn sources. These findings provide valuable insights into the application of organic Zn sources, specifically Zn-Lac and Zn-Gly, in the diets for grass carp and potentially for other fish species.https://www.mdpi.com/2076-3921/12/9/1664dietary Zn sourcesgrowthZn metabolismintestinal healthgrass carp |
| spellingShingle | Yi-Chuang Xu Hua Zheng Jia-Cheng Guo Xiao-Ying Tan Tao Zhao Yu-Feng Song Xiao-Lei Wei Zhi Luo Effects of Different Dietary Zinc (Zn) Sources on Growth Performance, Zn Metabolism, and Intestinal Health of Grass Carp Antioxidants dietary Zn sources growth Zn metabolism intestinal health grass carp |
| title | Effects of Different Dietary Zinc (Zn) Sources on Growth Performance, Zn Metabolism, and Intestinal Health of Grass Carp |
| title_full | Effects of Different Dietary Zinc (Zn) Sources on Growth Performance, Zn Metabolism, and Intestinal Health of Grass Carp |
| title_fullStr | Effects of Different Dietary Zinc (Zn) Sources on Growth Performance, Zn Metabolism, and Intestinal Health of Grass Carp |
| title_full_unstemmed | Effects of Different Dietary Zinc (Zn) Sources on Growth Performance, Zn Metabolism, and Intestinal Health of Grass Carp |
| title_short | Effects of Different Dietary Zinc (Zn) Sources on Growth Performance, Zn Metabolism, and Intestinal Health of Grass Carp |
| title_sort | effects of different dietary zinc zn sources on growth performance zn metabolism and intestinal health of grass carp |
| topic | dietary Zn sources growth Zn metabolism intestinal health grass carp |
| url | https://www.mdpi.com/2076-3921/12/9/1664 |
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