Return-to-Work Screening by Linear Discriminant Analysis of Heart Rate Variability Indices in Depressed Subjects
Using a linear discriminant analysis of heart rate variability (HRV) indices, the present study sought to verify the usefulness of autonomic measurement in major depressive disorder (MDD) patients by assessing the feasibility of their return to work after sick leave. When reinstatement was scheduled...
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MDPI AG
2021-07-01
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| Online Access: | https://www.mdpi.com/1424-8220/21/15/5177 |
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| author | Toshikazu Shinba Keizo Murotsu Yosuke Usui Yoshinori Andow Hiroshi Terada Nobutoshi Kariya Yoshitaka Tatebayashi Yoshiki Matsuda Go Mugishima Yujiro Shinba Guanghao Sun Takemi Matsui |
| author_facet | Toshikazu Shinba Keizo Murotsu Yosuke Usui Yoshinori Andow Hiroshi Terada Nobutoshi Kariya Yoshitaka Tatebayashi Yoshiki Matsuda Go Mugishima Yujiro Shinba Guanghao Sun Takemi Matsui |
| author_sort | Toshikazu Shinba |
| collection | DOAJ |
| description | Using a linear discriminant analysis of heart rate variability (HRV) indices, the present study sought to verify the usefulness of autonomic measurement in major depressive disorder (MDD) patients by assessing the feasibility of their return to work after sick leave. When reinstatement was scheduled, patients’ HRV was measured using a wearable electrocardiogram device. The outcome of the reinstatement was evaluated at one month after returning to work. HRV indices including high- and low-frequency components were calculated in three conditions within a session: initial rest, mental task, and rest after task. A linear discriminant function was made using the HRV indices of 30 MDD patients from our previous study to effectively discriminate the successful reinstatement from the unsuccessful reinstatement; this was then tested on 52 patients who participated in the present study. The discriminant function showed that the sensitivity and specificity in discriminating successful from unsuccessful returns were 95.8% and 35.7%, respectively. Sensitivity is high, indicating that normal HRV is required for a successful return, and that the discriminant analysis of HRV indices is useful for return-to-work screening in MDD patients. On the other hand, specificity is low, suggesting that other factors may also affect the outcome of reinstatement. |
| first_indexed | 2024-03-09T04:42:47Z |
| format | Article |
| id | doaj.art-34add042f0f14c60aa5901d255b87ae5 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-09T04:42:47Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-34add042f0f14c60aa5901d255b87ae52023-12-03T13:18:47ZengMDPI AGSensors1424-82202021-07-012115517710.3390/s21155177Return-to-Work Screening by Linear Discriminant Analysis of Heart Rate Variability Indices in Depressed SubjectsToshikazu Shinba0Keizo Murotsu1Yosuke Usui2Yoshinori Andow3Hiroshi Terada4Nobutoshi Kariya5Yoshitaka Tatebayashi6Yoshiki Matsuda7Go Mugishima8Yujiro Shinba9Guanghao Sun10Takemi Matsui11Department of Psychiatry, Shizuoka Saiseikai General Hospital, Shizuoka 422-8527, JapanDepartment of Psychiatry, Shizuoka Saiseikai General Hospital, Shizuoka 422-8527, JapanDepartment of Psychiatry, Shizuoka Red Cross Hospital, Shizuoka 420-0853, JapanYoga Mental Clinic, Tokyo 158-0097, JapanAoi Clinic, Shizuoka 420-0033, JapanMaynds Tower Mental Clinic, Tokyo 151-00053, JapanAffective Disorders Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, JapanAffective Disorders Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, JapanSchool of Human and Social Sciences, Fukuoka Prefectural University, Tagawa 825-8585, JapanAutonomic Nervous System Consulting, Shizuoka 420-0839, JapanGraduate School of Informatics and Engineering, The University of Electro-Communications, Tokyo 182-8585, JapanGraduate School of System Design, Tokyo Metropolitan University, Tokyo 191-0065, JapanUsing a linear discriminant analysis of heart rate variability (HRV) indices, the present study sought to verify the usefulness of autonomic measurement in major depressive disorder (MDD) patients by assessing the feasibility of their return to work after sick leave. When reinstatement was scheduled, patients’ HRV was measured using a wearable electrocardiogram device. The outcome of the reinstatement was evaluated at one month after returning to work. HRV indices including high- and low-frequency components were calculated in three conditions within a session: initial rest, mental task, and rest after task. A linear discriminant function was made using the HRV indices of 30 MDD patients from our previous study to effectively discriminate the successful reinstatement from the unsuccessful reinstatement; this was then tested on 52 patients who participated in the present study. The discriminant function showed that the sensitivity and specificity in discriminating successful from unsuccessful returns were 95.8% and 35.7%, respectively. Sensitivity is high, indicating that normal HRV is required for a successful return, and that the discriminant analysis of HRV indices is useful for return-to-work screening in MDD patients. On the other hand, specificity is low, suggesting that other factors may also affect the outcome of reinstatement.https://www.mdpi.com/1424-8220/21/15/5177depressionsick leavereturn-to-work screeningheart rate variabilitydiscriminant analysisautonomic dysregulation |
| spellingShingle | Toshikazu Shinba Keizo Murotsu Yosuke Usui Yoshinori Andow Hiroshi Terada Nobutoshi Kariya Yoshitaka Tatebayashi Yoshiki Matsuda Go Mugishima Yujiro Shinba Guanghao Sun Takemi Matsui Return-to-Work Screening by Linear Discriminant Analysis of Heart Rate Variability Indices in Depressed Subjects Sensors depression sick leave return-to-work screening heart rate variability discriminant analysis autonomic dysregulation |
| title | Return-to-Work Screening by Linear Discriminant Analysis of Heart Rate Variability Indices in Depressed Subjects |
| title_full | Return-to-Work Screening by Linear Discriminant Analysis of Heart Rate Variability Indices in Depressed Subjects |
| title_fullStr | Return-to-Work Screening by Linear Discriminant Analysis of Heart Rate Variability Indices in Depressed Subjects |
| title_full_unstemmed | Return-to-Work Screening by Linear Discriminant Analysis of Heart Rate Variability Indices in Depressed Subjects |
| title_short | Return-to-Work Screening by Linear Discriminant Analysis of Heart Rate Variability Indices in Depressed Subjects |
| title_sort | return to work screening by linear discriminant analysis of heart rate variability indices in depressed subjects |
| topic | depression sick leave return-to-work screening heart rate variability discriminant analysis autonomic dysregulation |
| url | https://www.mdpi.com/1424-8220/21/15/5177 |
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