Effects of endogenous nestin overexpression on proliferation, migration and MAPK signal transduction pathway in NIH3T3 cells

Effects of endogenous nestin overexpression on proliferation, migration and MAPK signal transduction pathway in NIH3T3 cells

Objective To observe the effects of endogenous nestin overexpression on the proliferation, migration and transforming growth factor β (TGF-β1)-induced expression of collagen and MAPK-related pathway in NIH3T3 fibroblasts. Methods CRISPR/SAM technique was used to construct a nestin-overexpressing cel...

Full description

Bibliographic Details
Main Authors:	HUANG Yuting, DONG Jinling, FENG Liyuan, LI Peng
Format:	Article
Language:	zho
Published:	Editorial Office of Journal of Third Military Medical University 2020-01-01
Series:	Di-san junyi daxue xuebao
Subjects:	nestin nih3t3 crispr/sam proliferation migration mitogen-activated protein kinase
Online Access:	http://aammt.tmmu.edu.cn/Upload/rhtml/201908194.htm

Similar Items

Heterogeneity of the NIH3T3 Fibroblast Cell Line
by: Amir Mohammad Rahimi, et al.
Published: (2022-08-01)

Increased expression of nestin in human pterygial epithelium
by: Hua Liu, et al.
Published: (2013-06-01)

Capacitance Contribution of NIH/3T3 Cells Existing on and between Electrodes of an Impedance Biosensor
by: Yeeun Kim, et al.
Published: (2023-11-01)

Panax ginseng total protein promotes proliferation and secretion of collagen in NIH/3T3 cells by activating extracellular signal-related kinase pathway
by: Xuenan Chen, et al.
Published: (2017-07-01)

Influence of DFG-STYK1/NOK on cell proliferation and G1/S distribution in mouse fibroblast cell line NIH3T3
by: CHEN Jian-miao
Published: (2021-06-01)

Cytotoxicity evaluation of haloperidol, clozapine and a new molecule with antipsychotic potential, PT-31, in NIH-3T3 cells
by: Juliana Machado Kayser, et al.
Published: (2023-05-01)

Nestin and Notch3 collaboratively regulate angiogenesis, collagen production, and endothelial–mesenchymal transition in lung endothelial cells
by: Wakako Daido, et al.
Published: (2023-09-01)

Cytotoxicity assay of fenugreek aqueous extract on NIH3T3 fibroblast cells
by: Ostad SN, et al.
Published: (2008-11-01)

Characterization of Betulinic Acid-Multiwalled Carbon Nanotubes Modified with Hydrophilic Biopolymer for Improved Biocompatibility on NIH/3T3 Cell Line
by: Julia Meihua Tan, et al.
Published: (2021-04-01)

Evaluation of Effects of Quercetin (3, 3’, 4’, 5, 7-pentohidroxyflavon) on Apoptosis and Telomerase Enzyme Activity in MCF-7 and NIH-3T3 Cell Lines Compared with Tamoxifen
by: Ayşe Ak, et al.
Published: (2011-09-01)

Investigating the cytotoxicity of the Ziziphus jujuba L., Ribes khorasanicum, Crocus sativus petal, and Centella asiatica extracts on the NIH/3T3 cell line
by: Samira Shahraki, et al.
Published: (2023-06-01)

Reactive oxygen species and senescence modulatory effects of rice bran extract on 4T1 and NIH-3T3 cells co-treatment with doxorubicin
by: Ummi Maryam Zulfin, et al.
Published: (2021-01-01)

Lipopolysaccharide Stimulated the Migration of NIH3T3 Cells Through a Positive Feedback Between β-Catenin and COX-2
by: Xiao-Jun Li, et al.
Published: (2018-12-01)

Nestin Expression Is Associated with Relapses in Head and Neck Lesions
by: Mario Pérez-Sayáns, et al.
Published: (2021-03-01)

Growth and Drug Interaction Monitoring of NIH 3T3 Cells by Image Analysis and Capacitive Biosensor
by: Gayoung Lee, et al.
Published: (2021-10-01)

Notch Signaling Enhances Nestin Expression in Gliomas
by: Alan H. Shih, et al.
Published: (2006-12-01)

A Nestin-cre transgenic mouse is insufficient for recombination in early embryonic neural progenitors
by: Huixuan Liang, et al.
Published: (2012-09-01)

Human Hair Keratin Composite Scaffold: Characterisation and Biocompatibility Study on NIH 3T3 Fibroblast Cells
by: Jamal Moideen Muthu Mohamed, et al.
Published: (2021-08-01)

Expression of Intermediate Filament Nestin in Blood Vessels of Neural and Non-neural Tissues
by: Jaroslav Mokrý, et al.
Published: (2008-01-01)

NIH3T3 Directs Memory-Fated CTL Programming and Represses High Expression of PD-1 on Antitumor CTLs
by: Yingyu Qin, et al.
Published: (2019-04-01)

Fibrotic effect of monoculture, conditioned media and coculture of fibroblast NIH3T3 cells on collagen secretion and mRNA TGF-β expressions
by: Rizki Awaluddin, et al.
Published: (2023-07-01)

Expression Pattern of the Cancer Stem Cell Marker “Nestin” in Leukoplakia and Oral Squamous Cell Carcinoma
by: Kushbu Narender Singh, et al.
Published: (2019-10-01)

Aberrant nestin expression during ethylnitrosourea-(ENU)-induced neurocarcinogenesis
by: Taichang Jang, et al.
Published: (2004-04-01)

Publishing Practices of NIH-Funded Faculty of MIT
by: Crummett, Courtney, et al.
Published: (2010)

Emerging biomarker in carcinogenesis. Focus on Nestin
by: Katarzyna Nowogrodzka, et al.
Published: (2022-12-01)

The Biological Role of Nestin(+)-Cells in Physiological and Pathological Cardiovascular Remodeling
by: Angelino Calderone, et al.
Published: (2018-02-01)

Evaluation of Clinical and Immunohistochemical Factors Relating to Melanoma Metastasis: Potential Roles of Nestin and Fascin in Melanoma
by: Yumiko Yamamoto, et al.
Published: (2022-01-01)

Recovery and maintenance of NESTIN expression in umbilical cord-MSC using a novel culture medium
by: Yuncheng Liu, et al.
Published: (2020-07-01)

Nestin expression associates with poor prognosis and triple negative phenotype in locally advanced (T4) breast cancer
by: F. Piras, et al.
Published: (2011-11-01)

Clozapine Increases Nestin Concentration in the Adult Male Rat Hippocampus: A Preliminary Study
by: Hakan Kayir, et al.
Published: (2022-03-01)

Nestin Expression Affects Resistance to Chemotherapy and Clinical Outcome in Small Cell Lung Cancer
by: Kazuki Sone, et al.
Published: (2020-08-01)

Hepatocellular carcinoma may display elevated nestin expression in endothelial cells: experimental study
by: Adriano Barreto Nogueira, et al.

TGF-β1 Increases Resistance of NIH/3T3 Fibroblasts Toward Apoptosis Through Activation of Smad2/3 and Erk1/2 Pathways
by: Ulugbek Negmadjanov, et al.
Published: (2016-11-01)

Nestin-Expressing Cells in the Lung: The Bad and the Good Parts
by: Gilberto Jaramillo-Rangel, et al.
Published: (2021-12-01)

Leadership of the ultimate interdisciplinary team: Rehabilitation science at NIH
by: Alison N. Cernich
Published: (2020-05-01)

Nestin Modulates Airway Smooth Muscle Cell Migration by Affecting Spatial Rearrangement of Vimentin Network and Focal Adhesion Assembly
by: Ruping Wang, et al.
Published: (2022-09-01)

Clinicopathological and prognostic significance of nestin expression in patients with breast cancer: a systematic review and meta-analysis
by: Xinyi Zhang, et al.
Published: (2020-05-01)

<it>MiR-125b</it> orchestrates cell proliferation, differentiation and migration in neural stem/progenitor cells by targeting <it>Nestin</it>
by: Cui Yi, et al.
Published: (2012-09-01)

Intermediate Filaments as Effectors of Cancer Development and Metastasis: A Focus on Keratins, Vimentin, and Nestin
by: Pooja Sharma, et al.
Published: (2019-05-01)

Nestin Improves Preeclampsia-Like Symptoms by Inhibiting Activity of Cyclin-Dependent Kinase 5
by: Xu Yang, et al.
Published: (2018-04-01)