Left ventricular remodelling in patients with reversible ischemic dysfunction before and after myocardial revascularization
Aim. To study the dynamics of left ventricular (LV) remodelling in patients with myocardial infarction (MI) and reversible ischemic dysfunction, before and after myocardial revascularization. Material and methods. The study included 69 patients after MI. All participants underwent two-dimensional ec...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
1970-01-01
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| Series: | Кардиоваскулярная терапия и профилактика |
| Subjects: | |
| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1991 |
| _version_ | 1797882863805267968 |
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| author | Kh. A. Mamatkulov A. L. Alyavi M. L. Kenzhaev D. A. Alimov S. R. Kenzhaev |
| author_facet | Kh. A. Mamatkulov A. L. Alyavi M. L. Kenzhaev D. A. Alimov S. R. Kenzhaev |
| author_sort | Kh. A. Mamatkulov |
| collection | DOAJ |
| description | Aim. To study the dynamics of left ventricular (LV) remodelling in patients with myocardial infarction (MI) and reversible ischemic dysfunction, before and after myocardial revascularization. Material and methods. The study included 69 patients after MI. All participants underwent two-dimensional echocardiography (EchoCG), within 24 hours after hospital admission and one month after revascularization. After three-four days of treatment and clinical stabilization, the patients underwent stress EchoCG with dobutamine, to assess myocardial viability. Results. Complete or partial recovery of all asynergic myocardial segments was observed in 22 (Group I) and 19 (Group II) patients, respectively, while in 28 (Group III), LV aneurysm was detected. In most patients from each group, transluminal balloon angioplasty (TLBAP) with stent implantation was performed. The proportion of conservatively treated patients was maximal in Group III. Despite revascularization, in coronary patients with impaired myocardial viability (Group III), the increase in ejection fraction and reduction in end-systolic volume was significantly lower than in patients with viable myocardium. Sphericity index, relative wall thickness index, and myocardial stress parameters were increased in each group, although this increase was non-significant in Group III. After revascularization, a significant reduction in end-systolic volume, and a tendency towards enddiastolic LV volume reduction were observed in each group, being maximal in Group I. Conclusion. In MI patients with viable myocardium in dyskineticLV zones, revascularization surgery should be considered. |
| first_indexed | 2024-04-10T03:41:25Z |
| format | Article |
| id | doaj.art-34b20f00e2534ffb91b71d99875b3ab7 |
| institution | Directory Open Access Journal |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| last_indexed | 2024-04-10T03:41:25Z |
| publishDate | 1970-01-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj.art-34b20f00e2534ffb91b71d99875b3ab72023-03-13T07:23:09Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01251970-01-0110728321703Left ventricular remodelling in patients with reversible ischemic dysfunction before and after myocardial revascularizationKh. A. Mamatkulov0A. L. Alyavi1M. L. Kenzhaev2D. A. Alimov3S. R. Kenzhaev4Ташкентская медицинская академияРеспубликанский научный центр экстренной медицинской помощи; Республиканский специализированный научно-практический медицинский центр терапии и медицинской реабилитацииРеспубликанский научный центр экстренной медицинской помощиРеспубликанский научный центр экстренной медицинской помощиРеспубликанский специализированный научно-практический медицинский центр терапии и медицинской реабилитацииAim. To study the dynamics of left ventricular (LV) remodelling in patients with myocardial infarction (MI) and reversible ischemic dysfunction, before and after myocardial revascularization. Material and methods. The study included 69 patients after MI. All participants underwent two-dimensional echocardiography (EchoCG), within 24 hours after hospital admission and one month after revascularization. After three-four days of treatment and clinical stabilization, the patients underwent stress EchoCG with dobutamine, to assess myocardial viability. Results. Complete or partial recovery of all asynergic myocardial segments was observed in 22 (Group I) and 19 (Group II) patients, respectively, while in 28 (Group III), LV aneurysm was detected. In most patients from each group, transluminal balloon angioplasty (TLBAP) with stent implantation was performed. The proportion of conservatively treated patients was maximal in Group III. Despite revascularization, in coronary patients with impaired myocardial viability (Group III), the increase in ejection fraction and reduction in end-systolic volume was significantly lower than in patients with viable myocardium. Sphericity index, relative wall thickness index, and myocardial stress parameters were increased in each group, although this increase was non-significant in Group III. After revascularization, a significant reduction in end-systolic volume, and a tendency towards enddiastolic LV volume reduction were observed in each group, being maximal in Group I. Conclusion. In MI patients with viable myocardium in dyskineticLV zones, revascularization surgery should be considered.https://cardiovascular.elpub.ru/jour/article/view/1991левый желудочекремоделированиедобутамининфаркт миокардареваскуляризация |
| spellingShingle | Kh. A. Mamatkulov A. L. Alyavi M. L. Kenzhaev D. A. Alimov S. R. Kenzhaev Left ventricular remodelling in patients with reversible ischemic dysfunction before and after myocardial revascularization Кардиоваскулярная терапия и профилактика левый желудочек ремоделирование добутамин инфаркт миокарда реваскуляризация |
| title | Left ventricular remodelling in patients with reversible ischemic dysfunction before and after myocardial revascularization |
| title_full | Left ventricular remodelling in patients with reversible ischemic dysfunction before and after myocardial revascularization |
| title_fullStr | Left ventricular remodelling in patients with reversible ischemic dysfunction before and after myocardial revascularization |
| title_full_unstemmed | Left ventricular remodelling in patients with reversible ischemic dysfunction before and after myocardial revascularization |
| title_short | Left ventricular remodelling in patients with reversible ischemic dysfunction before and after myocardial revascularization |
| title_sort | left ventricular remodelling in patients with reversible ischemic dysfunction before and after myocardial revascularization |
| topic | левый желудочек ремоделирование добутамин инфаркт миокарда реваскуляризация |
| url | https://cardiovascular.elpub.ru/jour/article/view/1991 |
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