Traditional uses, phytochemistry, and pharmacological properties of

Sophora alopecuroides L. , known as ku dou zi in China, has a long history as a traditional Chinese medicine for the treatment of bacillary dysentery, enteritis, hepatitis, and other diseases, and exerts a critical role in anti-tumor. It contains abundant of alkaloids such as oxymatrine, matrine, an...

Full description

Bibliographic Details
Main Authors: Yan-Xia Huang, Ge Wang, Jin-Shui Zhu, Rui Zhang, Jing Zhang
Format: Article
Language:English
Published: SAGE Publishing 2016-08-01
Series:European Journal of Inflammation
Online Access:https://doi.org/10.1177/1721727X16642779
_version_ 1828493493936324608
author Yan-Xia Huang
Ge Wang
Jin-Shui Zhu
Rui Zhang
Jing Zhang
author_facet Yan-Xia Huang
Ge Wang
Jin-Shui Zhu
Rui Zhang
Jing Zhang
author_sort Yan-Xia Huang
collection DOAJ
description Sophora alopecuroides L. , known as ku dou zi in China, has a long history as a traditional Chinese medicine for the treatment of bacillary dysentery, enteritis, hepatitis, and other diseases, and exerts a critical role in anti-tumor. It contains abundant of alkaloids such as oxymatrine, matrine, and total alkaloids, which have been developed in China as anti-disease drugs related with inhibition of the angiogenesis-associated factors, anti-inflammatory response, and regulation of JNK, p38 MAP kinase, and NF-κB signal pathways and so on. The purpose of this review is to take comprehensive summary of the botany, traditional uses, phytochemistry, and pharmacological properties of Sophora alopecuroides L. so as to provide opportunities for further study and clinical application.
first_indexed 2024-12-11T11:39:49Z
format Article
id doaj.art-34b4e06417e34b758ca2496c1ead5cff
institution Directory Open Access Journal
issn 1721-727X
language English
last_indexed 2024-12-11T11:39:49Z
publishDate 2016-08-01
publisher SAGE Publishing
record_format Article
series European Journal of Inflammation
spelling doaj.art-34b4e06417e34b758ca2496c1ead5cff2022-12-22T01:08:39ZengSAGE PublishingEuropean Journal of Inflammation1721-727X2016-08-011410.1177/1721727X16642779Traditional uses, phytochemistry, and pharmacological properties ofYan-Xia HuangGe WangJin-Shui ZhuRui ZhangJing ZhangSophora alopecuroides L. , known as ku dou zi in China, has a long history as a traditional Chinese medicine for the treatment of bacillary dysentery, enteritis, hepatitis, and other diseases, and exerts a critical role in anti-tumor. It contains abundant of alkaloids such as oxymatrine, matrine, and total alkaloids, which have been developed in China as anti-disease drugs related with inhibition of the angiogenesis-associated factors, anti-inflammatory response, and regulation of JNK, p38 MAP kinase, and NF-κB signal pathways and so on. The purpose of this review is to take comprehensive summary of the botany, traditional uses, phytochemistry, and pharmacological properties of Sophora alopecuroides L. so as to provide opportunities for further study and clinical application.https://doi.org/10.1177/1721727X16642779
spellingShingle Yan-Xia Huang
Ge Wang
Jin-Shui Zhu
Rui Zhang
Jing Zhang
Traditional uses, phytochemistry, and pharmacological properties of
European Journal of Inflammation
title Traditional uses, phytochemistry, and pharmacological properties of
title_full Traditional uses, phytochemistry, and pharmacological properties of
title_fullStr Traditional uses, phytochemistry, and pharmacological properties of
title_full_unstemmed Traditional uses, phytochemistry, and pharmacological properties of
title_short Traditional uses, phytochemistry, and pharmacological properties of
title_sort traditional uses phytochemistry and pharmacological properties of
url https://doi.org/10.1177/1721727X16642779
work_keys_str_mv AT yanxiahuang traditionalusesphytochemistryandpharmacologicalpropertiesof
AT gewang traditionalusesphytochemistryandpharmacologicalpropertiesof
AT jinshuizhu traditionalusesphytochemistryandpharmacologicalpropertiesof
AT ruizhang traditionalusesphytochemistryandpharmacologicalpropertiesof
AT jingzhang traditionalusesphytochemistryandpharmacologicalpropertiesof