The Statin Target HMG-Coenzyme a Reductase (Hmgcr) Regulates Sleep Homeostasis in <i>Drosophila</i>

Statins, HMG Coenzyme A Reductase (HMGCR) inhibitors, are a first-line therapy, used to reduce hypercholesterolemia and the risk for cardiovascular events. While sleep disturbances are recognized as a side-effect of statin treatment, the impact of statins on sleep is under debate. Using Drosophila,...

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Bibliographic Details
Main Authors: Ahmed M. Alsehli, Sifang Liao, Mohamed H. Al-Sabri, Lukas Vasionis, Archana Purohit, Neha Behare, Laura E. Clemensson, Michael J. Williams, Helgi B. Schiöth
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/15/1/79