The effect of caffeine on orthodontic tooth movement in rats

Objective(s): to determine the effect of different doses of caffeine on orthodontic tooth movement (OTM) in rats. Materials and Methods: Forty male 250-300 g Sprague-Dawley rats were randomly divided into four groups of ten animals each and received 0 (control), 1 g/l, 2 g/l and 3 g/l caffeine in ta...

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Main Authors: Mohsen Shirazi, Hamed Vaziri, Behzad Salari, Pouria Motahhari, Shahroo Etemad-Moghadam, Ahmad Reza Dehpour
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2017-03-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/article_8353_d3284eb83e5a352fc2bf27a848c8a1f8.pdf
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author Mohsen Shirazi
Hamed Vaziri
Behzad Salari
Pouria Motahhari
Shahroo Etemad-Moghadam
Ahmad Reza Dehpour
author_facet Mohsen Shirazi
Hamed Vaziri
Behzad Salari
Pouria Motahhari
Shahroo Etemad-Moghadam
Ahmad Reza Dehpour
author_sort Mohsen Shirazi
collection DOAJ
description Objective(s): to determine the effect of different doses of caffeine on orthodontic tooth movement (OTM) in rats. Materials and Methods: Forty male 250-300 g Sprague-Dawley rats were randomly divided into four groups of ten animals each and received 0 (control), 1 g/l, 2 g/l and 3 g/l caffeine in tap water for 3 days. Orthodontic appliances were ligated between the maxillary first molars and incisors on the 4th day of the study period. All rats were sacrificed after 2 weeks of treatment after which OTM was measured. Hematoxylin/eosin-stained sections of the molars were prepared and the mesial roots were examined for resorption-lacunae depth and osteoclast number. ANOVA was used for statistical analysis (P
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spelling doaj.art-34c9cae9319e4ac5ae74de05cd7754372022-12-21T19:50:53ZengMashhad University of Medical SciencesIranian Journal of Basic Medical Sciences2008-38662008-38742017-03-0120326026410.22038/ijbms.2017.83538353The effect of caffeine on orthodontic tooth movement in ratsMohsen Shirazi0Hamed Vaziri1Behzad Salari2Pouria Motahhari3Shahroo Etemad-Moghadam4Ahmad Reza Dehpour5Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran|Department of Orthodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, IranPrivate practice, Houston, TexasOrthodontic Resident, Department of Orthodontics, School of Dentistry, Qazvin University of Medical Sciences, Qazvin, IranDepartment of Oral and Maxillofacial Pathology, Tehran University of Medical Sciences, Tehran, IranDental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, IranExperimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran|Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, IranObjective(s): to determine the effect of different doses of caffeine on orthodontic tooth movement (OTM) in rats. Materials and Methods: Forty male 250-300 g Sprague-Dawley rats were randomly divided into four groups of ten animals each and received 0 (control), 1 g/l, 2 g/l and 3 g/l caffeine in tap water for 3 days. Orthodontic appliances were ligated between the maxillary first molars and incisors on the 4th day of the study period. All rats were sacrificed after 2 weeks of treatment after which OTM was measured. Hematoxylin/eosin-stained sections of the molars were prepared and the mesial roots were examined for resorption-lacunae depth and osteoclast number. ANOVA was used for statistical analysis (Phttp://ijbms.mums.ac.ir/article_8353_d3284eb83e5a352fc2bf27a848c8a1f8.pdfCaffeineRatsRoot resorptionTooth movement
spellingShingle Mohsen Shirazi
Hamed Vaziri
Behzad Salari
Pouria Motahhari
Shahroo Etemad-Moghadam
Ahmad Reza Dehpour
The effect of caffeine on orthodontic tooth movement in rats
Iranian Journal of Basic Medical Sciences
Caffeine
Rats
Root resorption
Tooth movement
title The effect of caffeine on orthodontic tooth movement in rats
title_full The effect of caffeine on orthodontic tooth movement in rats
title_fullStr The effect of caffeine on orthodontic tooth movement in rats
title_full_unstemmed The effect of caffeine on orthodontic tooth movement in rats
title_short The effect of caffeine on orthodontic tooth movement in rats
title_sort effect of caffeine on orthodontic tooth movement in rats
topic Caffeine
Rats
Root resorption
Tooth movement
url http://ijbms.mums.ac.ir/article_8353_d3284eb83e5a352fc2bf27a848c8a1f8.pdf
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