Evaluation of five screening tests licensed in Argentina for detection of hepatitis C virus antibodies
This study was conducted to compare among the most recent generation of five screening tests licensed in Argentina, in order to evaluate which of the tests has the best sensitivity for detection of antibodies against hepatitis C virus (HCV). The tests analyzed were: Detect-HCV™ (3.0) Bioch...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
2005-05-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000300016 |
| _version_ | 1797718279441088512 |
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| author | Viviana Ré Sandra Gallego Elena Treviño Gabriela Barbás Claudia Domínguez Osvaldo Elbarcha Héctor Bepre Marta Contigiani |
| author_facet | Viviana Ré Sandra Gallego Elena Treviño Gabriela Barbás Claudia Domínguez Osvaldo Elbarcha Héctor Bepre Marta Contigiani |
| author_sort | Viviana Ré |
| collection | DOAJ |
| description | This study was conducted to compare among the most recent generation of five screening tests licensed in Argentina, in order to evaluate which of the tests has the best sensitivity for detection of antibodies against hepatitis C virus (HCV). The tests analyzed were: Detect-HCV™ (3.0) Biochem ImmunoSystems, Canada; Hepatitis C EIA Wiener Lab., Argentina; Equipar HCV Ab, Italy; Murex HCV 4.0, UK and Serodia-HCV particles agglutination test, Japan. The results obtained showed high discrepancy between the different kits used and show that some of the tests assessed have a low sensitivity for anti-HCV detection in both chronic infections and early seroconversion, and indicate that among the commercially available kits in Argentina, Murex HCV 4.0 (UK) and Serodia-HCV particles agglutination test (Japan) have the best sensitivity for HCV screening. Although the sensitivity of the assays is the first parameter to be considered for blood screening, more studies should be carried out to assess the specificity of such assays. |
| first_indexed | 2024-03-12T08:48:34Z |
| format | Article |
| id | doaj.art-34caf10c8d544af8afb7f144366d513a |
| institution | Directory Open Access Journal |
| issn | 0074-0276 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T08:48:34Z |
| publishDate | 2005-05-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-34caf10c8d544af8afb7f144366d513a2023-09-02T16:22:13ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80602005-05-01100330330710.1590/S0074-02762005000300016Evaluation of five screening tests licensed in Argentina for detection of hepatitis C virus antibodiesViviana RéSandra GallegoElena TreviñoGabriela BarbásClaudia DomínguezOsvaldo ElbarchaHéctor BepreMarta ContigianiThis study was conducted to compare among the most recent generation of five screening tests licensed in Argentina, in order to evaluate which of the tests has the best sensitivity for detection of antibodies against hepatitis C virus (HCV). The tests analyzed were: Detect-HCV™ (3.0) Biochem ImmunoSystems, Canada; Hepatitis C EIA Wiener Lab., Argentina; Equipar HCV Ab, Italy; Murex HCV 4.0, UK and Serodia-HCV particles agglutination test, Japan. The results obtained showed high discrepancy between the different kits used and show that some of the tests assessed have a low sensitivity for anti-HCV detection in both chronic infections and early seroconversion, and indicate that among the commercially available kits in Argentina, Murex HCV 4.0 (UK) and Serodia-HCV particles agglutination test (Japan) have the best sensitivity for HCV screening. Although the sensitivity of the assays is the first parameter to be considered for blood screening, more studies should be carried out to assess the specificity of such assays.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000300016hepatitis C virus (HCV)HCV screening testsensitivity |
| spellingShingle | Viviana Ré Sandra Gallego Elena Treviño Gabriela Barbás Claudia Domínguez Osvaldo Elbarcha Héctor Bepre Marta Contigiani Evaluation of five screening tests licensed in Argentina for detection of hepatitis C virus antibodies Memorias do Instituto Oswaldo Cruz hepatitis C virus (HCV) HCV screening test sensitivity |
| title | Evaluation of five screening tests licensed in Argentina for detection of hepatitis C virus antibodies |
| title_full | Evaluation of five screening tests licensed in Argentina for detection of hepatitis C virus antibodies |
| title_fullStr | Evaluation of five screening tests licensed in Argentina for detection of hepatitis C virus antibodies |
| title_full_unstemmed | Evaluation of five screening tests licensed in Argentina for detection of hepatitis C virus antibodies |
| title_short | Evaluation of five screening tests licensed in Argentina for detection of hepatitis C virus antibodies |
| title_sort | evaluation of five screening tests licensed in argentina for detection of hepatitis c virus antibodies |
| topic | hepatitis C virus (HCV) HCV screening test sensitivity |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000300016 |
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