The Human Systemic and Cerebral Circulations: Contrasts in Structure and Function
Apart from peculiarities of the cerebral circulation, required to perfuse the brain with the subject erect, the principles established for function of the human systemic circulation (pulsatile flow at input and steady flow at output in capillaries) are identical to those established for other mammal...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2020-07-01
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| Series: | Artery Research |
| Subjects: | |
| Online Access: | https://www.atlantis-press.com/article/125941884/view |
| _version_ | 1818038021202640896 |
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| author | Michael O’Rourke Jonathan Stone Audrey Adji Mi Ok Kim Yan Li Ji Guang Wang Alberto Avolio Per Kristian Eide Marek Czosnyka |
| author_facet | Michael O’Rourke Jonathan Stone Audrey Adji Mi Ok Kim Yan Li Ji Guang Wang Alberto Avolio Per Kristian Eide Marek Czosnyka |
| author_sort | Michael O’Rourke |
| collection | DOAJ |
| description | Apart from peculiarities of the cerebral circulation, required to perfuse the brain with the subject erect, the principles established for function of the human systemic circulation (pulsatile flow at input and steady flow at output in capillaries) are identical to those established for other mammals. Assumption of the erect posture first as Homo erectus, then as Homo sapiens, conferred huge advantage to humans and led to command of the mammalian kingdom. But this required a circulation which could perfuse the brain securely against gravity in all positions of the body. This review covers what presently is known about the human cerebral circulation, and how such knowledge can be applied in some clinical conditions including development of dementia in older subjects, and in management of patients with elevation of intra-cranial pressure in younger subjects. |
| first_indexed | 2024-12-10T07:36:07Z |
| format | Article |
| id | doaj.art-34ccff35d7214590bf6c89934af86e88 |
| institution | Directory Open Access Journal |
| issn | 1876-4401 |
| language | English |
| last_indexed | 2024-12-10T07:36:07Z |
| publishDate | 2020-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Artery Research |
| spelling | doaj.art-34ccff35d7214590bf6c89934af86e882022-12-22T01:57:25ZengBMCArtery Research1876-44012020-07-0126410.2991/artres.k.200704.001The Human Systemic and Cerebral Circulations: Contrasts in Structure and FunctionMichael O’RourkeJonathan StoneAudrey AdjiMi Ok KimYan LiJi Guang WangAlberto AvolioPer Kristian EideMarek CzosnykaApart from peculiarities of the cerebral circulation, required to perfuse the brain with the subject erect, the principles established for function of the human systemic circulation (pulsatile flow at input and steady flow at output in capillaries) are identical to those established for other mammals. Assumption of the erect posture first as Homo erectus, then as Homo sapiens, conferred huge advantage to humans and led to command of the mammalian kingdom. But this required a circulation which could perfuse the brain securely against gravity in all positions of the body. This review covers what presently is known about the human cerebral circulation, and how such knowledge can be applied in some clinical conditions including development of dementia in older subjects, and in management of patients with elevation of intra-cranial pressure in younger subjects.https://www.atlantis-press.com/article/125941884/viewWave reflectionreflection coefficientpressure wavesflow wavesintracranial pressurepulse wave analysis |
| spellingShingle | Michael O’Rourke Jonathan Stone Audrey Adji Mi Ok Kim Yan Li Ji Guang Wang Alberto Avolio Per Kristian Eide Marek Czosnyka The Human Systemic and Cerebral Circulations: Contrasts in Structure and Function Artery Research Wave reflection reflection coefficient pressure waves flow waves intracranial pressure pulse wave analysis |
| title | The Human Systemic and Cerebral Circulations: Contrasts in Structure and Function |
| title_full | The Human Systemic and Cerebral Circulations: Contrasts in Structure and Function |
| title_fullStr | The Human Systemic and Cerebral Circulations: Contrasts in Structure and Function |
| title_full_unstemmed | The Human Systemic and Cerebral Circulations: Contrasts in Structure and Function |
| title_short | The Human Systemic and Cerebral Circulations: Contrasts in Structure and Function |
| title_sort | human systemic and cerebral circulations contrasts in structure and function |
| topic | Wave reflection reflection coefficient pressure waves flow waves intracranial pressure pulse wave analysis |
| url | https://www.atlantis-press.com/article/125941884/view |
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