Assessment of bicuspid aortic valve phenotypes and associated pathologies: A transesophageal echocardiographic study
Objective: We investigated the frequency of different bicuspid aortic valve disease (BAV) phenotypes,the associated valvular pathologies, and the aortopathy phenotypes, using 2-dimensional (2D) transthoracic, 2D transesophageal echocardiography (TEE) and 3-dimensional (3D) TEE. Methods: A total of 1...
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| Format: | Article |
| Language: | English |
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KARE Publishing
2017-12-01
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| Series: | Türk Kardiyoloji Derneği Arşivi |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-03152 |
| _version_ | 1797907006030348288 |
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| author | Selcen Yakar Tülüce Kamil Tülüce Ersin Çağrı Şimşek Özgen Şafak Mehmet Şefa Ökten Zeynep Yapan Emren Sadık Volkan Emren Uğur Kocabaş Serdar Bayata Cem Nazlı |
| author_facet | Selcen Yakar Tülüce Kamil Tülüce Ersin Çağrı Şimşek Özgen Şafak Mehmet Şefa Ökten Zeynep Yapan Emren Sadık Volkan Emren Uğur Kocabaş Serdar Bayata Cem Nazlı |
| author_sort | Selcen Yakar Tülüce |
| collection | DOAJ |
| description | Objective: We investigated the frequency of different bicuspid aortic valve disease (BAV) phenotypes,the associated valvular pathologies, and the aortopathy phenotypes, using 2-dimensional (2D) transthoracic, 2D transesophageal echocardiography (TEE) and 3-dimensional (3D) TEE.
Methods: A total of 154 patients with BAV were included. Five BAV phenotypes were detected. To better define valvular pathologies, binary classifications of BAV were used: BAV with antero-posterior commisural line (BAV-AP) and right-left commissural line (BAV-RL). Aortopathy phenotype was classified according to the involved tract(s).
Results: Of the patients, 53.2% had type 1, 16.2% type 2, 15.6% type 3, 1.3% type 4, and 13.6% had type 5 BAV. The prevalence of BAV-AP and BAV-RL was 68.2% and 31.8%, respectively. No difference was detected with respect to aortic regurgitation between BAV-AP and BAV-RL (p=0.9), but the BAV-RL group had an increased propensity to have a stenotic aortic valve (p=0.003). The indexed aortic diameter was larger in BAV-AP cases than BAV-RL at the sinus of Valsalva (p=0.008). In patients with dilatation of the root and tubular portion, a predominance of BAV-AP versus BAV-RL was observed (85% vs 15%). A markedly low prevalence of the root phenotype (3.2%) was observed. In 90.1% of the patients, 2D TEE was sufficient to classify BAV phenotypes; further 3D imaging was needed in 9.9% of the cases.
Conclusion: There may be racial differences in the frequency of valvular and aortopathy phenotypes in patients with BAV. BAV phenotypes differ with respect to aortic stenosis and aortopathy phenotypes. TEE may have good diagnostic utility in differentiating BAV phenotypes. |
| first_indexed | 2024-04-10T10:29:41Z |
| format | Article |
| id | doaj.art-34d3ce8b39df4c8989380894b52b525c |
| institution | Directory Open Access Journal |
| issn | 1016-5169 |
| language | English |
| last_indexed | 2024-04-10T10:29:41Z |
| publishDate | 2017-12-01 |
| publisher | KARE Publishing |
| record_format | Article |
| series | Türk Kardiyoloji Derneği Arşivi |
| spelling | doaj.art-34d3ce8b39df4c8989380894b52b525c2023-02-15T16:21:10ZengKARE PublishingTürk Kardiyoloji Derneği Arşivi1016-51692017-12-0145869070110.5543/tkda.2017.03152TKDA-03152Assessment of bicuspid aortic valve phenotypes and associated pathologies: A transesophageal echocardiographic studySelcen Yakar Tülüce0Kamil Tülüce1Ersin Çağrı Şimşek2Özgen Şafak3Mehmet Şefa Ökten4Zeynep Yapan Emren5Sadık Volkan Emren6Uğur Kocabaş7Serdar Bayata8Cem Nazlı9Department of Cardiology, İzmir Katip Çelebi University Atatürk Training and Research Hospital, İzmir, TurkeyDepartment of Cardiology, Tepecik Training and Research Hospital, İzmir, TurkeyDepartment of Cardiology, İzmir Katip Çelebi University Atatürk Training and Research Hospital, İzmir, TurkeyDepartment of Cardiology, İzmir Katip Çelebi University Atatürk Training and Research Hospital, İzmir, TurkeyDepartment of Cardiology, Ege University Faculty of Medicine, İzmir, TurkeyDepartment of Cardiology, Tepecik Training and Research Hospital, İzmir, TurkeyDepartment of Cardiology, İzmir Katip Çelebi University Atatürk Training and Research Hospital, İzmir, TurkeyDepartment of Cardiology, İzmir Katip Çelebi University Atatürk Training and Research Hospital, İzmir, TurkeyDepartment of Cardiology, İzmir Katip Çelebi University Atatürk Training and Research Hospital, İzmir, TurkeyDepartment of Cardiology, İzmir Katip Çelebi University Atatürk Training and Research Hospital, İzmir, TurkeyObjective: We investigated the frequency of different bicuspid aortic valve disease (BAV) phenotypes,the associated valvular pathologies, and the aortopathy phenotypes, using 2-dimensional (2D) transthoracic, 2D transesophageal echocardiography (TEE) and 3-dimensional (3D) TEE. Methods: A total of 154 patients with BAV were included. Five BAV phenotypes were detected. To better define valvular pathologies, binary classifications of BAV were used: BAV with antero-posterior commisural line (BAV-AP) and right-left commissural line (BAV-RL). Aortopathy phenotype was classified according to the involved tract(s). Results: Of the patients, 53.2% had type 1, 16.2% type 2, 15.6% type 3, 1.3% type 4, and 13.6% had type 5 BAV. The prevalence of BAV-AP and BAV-RL was 68.2% and 31.8%, respectively. No difference was detected with respect to aortic regurgitation between BAV-AP and BAV-RL (p=0.9), but the BAV-RL group had an increased propensity to have a stenotic aortic valve (p=0.003). The indexed aortic diameter was larger in BAV-AP cases than BAV-RL at the sinus of Valsalva (p=0.008). In patients with dilatation of the root and tubular portion, a predominance of BAV-AP versus BAV-RL was observed (85% vs 15%). A markedly low prevalence of the root phenotype (3.2%) was observed. In 90.1% of the patients, 2D TEE was sufficient to classify BAV phenotypes; further 3D imaging was needed in 9.9% of the cases. Conclusion: There may be racial differences in the frequency of valvular and aortopathy phenotypes in patients with BAV. BAV phenotypes differ with respect to aortic stenosis and aortopathy phenotypes. TEE may have good diagnostic utility in differentiating BAV phenotypes.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-03152aortopathybicuspid aortic valve; transesophageal echocardiography. |
| spellingShingle | Selcen Yakar Tülüce Kamil Tülüce Ersin Çağrı Şimşek Özgen Şafak Mehmet Şefa Ökten Zeynep Yapan Emren Sadık Volkan Emren Uğur Kocabaş Serdar Bayata Cem Nazlı Assessment of bicuspid aortic valve phenotypes and associated pathologies: A transesophageal echocardiographic study Türk Kardiyoloji Derneği Arşivi aortopathy bicuspid aortic valve; transesophageal echocardiography. |
| title | Assessment of bicuspid aortic valve phenotypes and associated pathologies: A transesophageal echocardiographic study |
| title_full | Assessment of bicuspid aortic valve phenotypes and associated pathologies: A transesophageal echocardiographic study |
| title_fullStr | Assessment of bicuspid aortic valve phenotypes and associated pathologies: A transesophageal echocardiographic study |
| title_full_unstemmed | Assessment of bicuspid aortic valve phenotypes and associated pathologies: A transesophageal echocardiographic study |
| title_short | Assessment of bicuspid aortic valve phenotypes and associated pathologies: A transesophageal echocardiographic study |
| title_sort | assessment of bicuspid aortic valve phenotypes and associated pathologies a transesophageal echocardiographic study |
| topic | aortopathy bicuspid aortic valve; transesophageal echocardiography. |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-03152 |
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