Overview of the Analytes Applied in Genotypic HIV Drug Resistance Testing
The close monitoring of HIV drug resistance using genotypic HIV drug resistance testing (HIVDRT) has become essential for effective HIV/AIDS management at both individual and population levels. Over the years, a broad spectrum of analytes or specimens have been applied or attempted in HIVDRT; howeve...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/11/7/739 |
| _version_ | 1797433238876061696 |
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| author | Hezhao Ji Paul Sandstrom |
| author_facet | Hezhao Ji Paul Sandstrom |
| author_sort | Hezhao Ji |
| collection | DOAJ |
| description | The close monitoring of HIV drug resistance using genotypic HIV drug resistance testing (HIVDRT) has become essential for effective HIV/AIDS management at both individual and population levels. Over the years, a broad spectrum of analytes or specimens have been applied or attempted in HIVDRT; however, the suitability and performance of these analytes in HIVDRT and the clinical relevance of the results from them may vary significantly. This article provides a focused overview of the performance, strengths, and weaknesses of various analytes while used in HIVDRT, which may inform the optimal analytes selection in different application contexts. |
| first_indexed | 2024-03-09T10:13:13Z |
| format | Article |
| id | doaj.art-34d7cafe5e7a4a6d918aa051b3a270ef |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-09T10:13:13Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-34d7cafe5e7a4a6d918aa051b3a270ef2023-12-01T22:32:33ZengMDPI AGPathogens2076-08172022-06-0111773910.3390/pathogens11070739Overview of the Analytes Applied in Genotypic HIV Drug Resistance TestingHezhao Ji0Paul Sandstrom1National Microbiology Laboratory at JC Wilt Infectious Diseases Research Centre, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, CanadaNational Microbiology Laboratory at JC Wilt Infectious Diseases Research Centre, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, CanadaThe close monitoring of HIV drug resistance using genotypic HIV drug resistance testing (HIVDRT) has become essential for effective HIV/AIDS management at both individual and population levels. Over the years, a broad spectrum of analytes or specimens have been applied or attempted in HIVDRT; however, the suitability and performance of these analytes in HIVDRT and the clinical relevance of the results from them may vary significantly. This article provides a focused overview of the performance, strengths, and weaknesses of various analytes while used in HIVDRT, which may inform the optimal analytes selection in different application contexts.https://www.mdpi.com/2076-0817/11/7/739HIVdrug resistancetestinganalytesspecimensperformance |
| spellingShingle | Hezhao Ji Paul Sandstrom Overview of the Analytes Applied in Genotypic HIV Drug Resistance Testing Pathogens HIV drug resistance testing analytes specimens performance |
| title | Overview of the Analytes Applied in Genotypic HIV Drug Resistance Testing |
| title_full | Overview of the Analytes Applied in Genotypic HIV Drug Resistance Testing |
| title_fullStr | Overview of the Analytes Applied in Genotypic HIV Drug Resistance Testing |
| title_full_unstemmed | Overview of the Analytes Applied in Genotypic HIV Drug Resistance Testing |
| title_short | Overview of the Analytes Applied in Genotypic HIV Drug Resistance Testing |
| title_sort | overview of the analytes applied in genotypic hiv drug resistance testing |
| topic | HIV drug resistance testing analytes specimens performance |
| url | https://www.mdpi.com/2076-0817/11/7/739 |
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