Hypoxia regulates Notch-3 mRNA and receptor activation in prostate cancer cells

Hypoxia regulates Notch-3 mRNA and receptor activation in prostate cancer cells

The Notch-3 receptor is a recognized key regulator of vascular responses and is increasingly associated with tumorigenesis. Hypoxia-inducible factors activate specific signaling pathways such as Notch in a number of cellular models. This study aimed to evaluate the regulation of Notch-3 by hypoxia i...

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Bibliographic Details
Main Authors: Armelle Meunier, Angela Nilda Flores, Niamh McDermott, Karla Rivera-Figueroa, Antoinette Perry, Thomas Lynch, Kathrine Røe Redalen, Laure Marignol
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Heliyon
Subjects:
Medicine
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844015305442

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