The α6 GABA<sub>A</sub> Receptor Positive Allosteric Modulator DK-I-56-1 Reduces Tic-Related Behaviors in Mouse Models of Tourette Syndrome

The α6 GABA<sub>A</sub> Receptor Positive Allosteric Modulator DK-I-56-1 Reduces Tic-Related Behaviors in Mouse Models of Tourette Syndrome

Tourette syndrome (TS) is a disabling neurodevelopmental disorder characterized by multiple, recurrent tics. The pharmacological treatment of TS is currently based on dopaminergic antagonists; however, these drugs are associated with extrapyramidal symptoms and other serious adverse events. Recent e...

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Príomhchruthaitheoirí: Roberto Cadeddu, Daniel E. Knutson, Laura J. Mosher, Stefanos Loizou, Karen Odeh, Janet L. Fisher, James M. Cook, Marco Bortolato
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: MDPI AG 2021-01-01
Sraith:Biomolecules
Ábhair:
DK-I-56-1
Tourette syndrome
tics
spontaneous eyeblinks
GABA<sub>A</sub> receptor
Rochtain ar líne:https://www.mdpi.com/2218-273X/11/2/175

Ar líne

https://www.mdpi.com/2218-273X/11/2/175

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