Analgesic Efficacy of Quadratus Lumborum Block in Infants Undergoing Pyeloplasty

Post-operative analgesic management is challenging in infants and opioids have been the standard of care. However, they are associated with adverse effects which may negatively impact infants. In this retrospective cohort study, we sought to explore the postoperative analgesic efficacy of quadratus...

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Main Authors: Paul F. Chisolm, Nikhi P. Singh, Ian Cummins, Robert A. Oster, Damon Cox, Pankaj P. Dangle
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Surgeries
Subjects:
Online Access:https://www.mdpi.com/2673-4095/2/3/28
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author Paul F. Chisolm
Nikhi P. Singh
Ian Cummins
Robert A. Oster
Damon Cox
Pankaj P. Dangle
author_facet Paul F. Chisolm
Nikhi P. Singh
Ian Cummins
Robert A. Oster
Damon Cox
Pankaj P. Dangle
author_sort Paul F. Chisolm
collection DOAJ
description Post-operative analgesic management is challenging in infants and opioids have been the standard of care. However, they are associated with adverse effects which may negatively impact infants. In this retrospective cohort study, we sought to explore the postoperative analgesic efficacy of quadratus lumborum (QL) block in the infant population undergoing dorsal lumbotomy pyeloplasty. Chart review of 34 infants (≤12 months) who underwent dorsal lumbotomy pyeloplasty between 2016–2020 was performed. Post-operative pain was assessed using externally validated pain scales (CRIES & FLACC) and monitored hemodynamics (pulse and blood pressure). Opioid doses were standardized by using morphine milligram equivalency (MME). The Prescription Database Monitoring Program (PDMP) was utilized to determine if discharge opioid prescriptions were filled. Of 34 patients, 13 received the QL block. Mean age at the time of surgery was 6.2 months ± 3.2 months. The QL group received 0.8 MME postoperatively, whereas the non-QL group received 0.9 MME (<i>p</i> = 0.82). The QL group (20%) filled their discharge opioid prescription less frequently compared to non-QL group (100%) (<i>p</i> = 0.002). There were no observed differences between pain scale or hemodynamic variables. Further studies are warranted to explore QL block’s efficacy for post-operative infant pain management.
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spelling doaj.art-34dfffd1db2a43b9bb182cda0423cd6f2023-11-22T15:18:35ZengMDPI AGSurgeries2673-40952021-08-012327828510.3390/surgeries2030028Analgesic Efficacy of Quadratus Lumborum Block in Infants Undergoing PyeloplastyPaul F. Chisolm0Nikhi P. Singh1Ian Cummins2Robert A. Oster3Damon Cox4Pankaj P. Dangle5School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USASchool of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USASchool of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USASchool of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USADepartment of Anesthesiology, Children’s of Alabama, Birmingham, AL 35294, USADepartment of Urology, University of Alabama at Birmingham, Birmingham, AL 35294, USAPost-operative analgesic management is challenging in infants and opioids have been the standard of care. However, they are associated with adverse effects which may negatively impact infants. In this retrospective cohort study, we sought to explore the postoperative analgesic efficacy of quadratus lumborum (QL) block in the infant population undergoing dorsal lumbotomy pyeloplasty. Chart review of 34 infants (≤12 months) who underwent dorsal lumbotomy pyeloplasty between 2016–2020 was performed. Post-operative pain was assessed using externally validated pain scales (CRIES & FLACC) and monitored hemodynamics (pulse and blood pressure). Opioid doses were standardized by using morphine milligram equivalency (MME). The Prescription Database Monitoring Program (PDMP) was utilized to determine if discharge opioid prescriptions were filled. Of 34 patients, 13 received the QL block. Mean age at the time of surgery was 6.2 months ± 3.2 months. The QL group received 0.8 MME postoperatively, whereas the non-QL group received 0.9 MME (<i>p</i> = 0.82). The QL group (20%) filled their discharge opioid prescription less frequently compared to non-QL group (100%) (<i>p</i> = 0.002). There were no observed differences between pain scale or hemodynamic variables. Further studies are warranted to explore QL block’s efficacy for post-operative infant pain management.https://www.mdpi.com/2673-4095/2/3/28pediatric urologypyeloplastynerve blockquadratus lumborum block
spellingShingle Paul F. Chisolm
Nikhi P. Singh
Ian Cummins
Robert A. Oster
Damon Cox
Pankaj P. Dangle
Analgesic Efficacy of Quadratus Lumborum Block in Infants Undergoing Pyeloplasty
Surgeries
pediatric urology
pyeloplasty
nerve block
quadratus lumborum block
title Analgesic Efficacy of Quadratus Lumborum Block in Infants Undergoing Pyeloplasty
title_full Analgesic Efficacy of Quadratus Lumborum Block in Infants Undergoing Pyeloplasty
title_fullStr Analgesic Efficacy of Quadratus Lumborum Block in Infants Undergoing Pyeloplasty
title_full_unstemmed Analgesic Efficacy of Quadratus Lumborum Block in Infants Undergoing Pyeloplasty
title_short Analgesic Efficacy of Quadratus Lumborum Block in Infants Undergoing Pyeloplasty
title_sort analgesic efficacy of quadratus lumborum block in infants undergoing pyeloplasty
topic pediatric urology
pyeloplasty
nerve block
quadratus lumborum block
url https://www.mdpi.com/2673-4095/2/3/28
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AT robertaoster analgesicefficacyofquadratuslumborumblockininfantsundergoingpyeloplasty
AT damoncox analgesicefficacyofquadratuslumborumblockininfantsundergoingpyeloplasty
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