Effect of Mirabegron on Intraocular Pressure in Patients with Glaucoma

Objective:Assessment of the effects of mirabegron treatment used for overactive bladder (OAB) symptoms in glaucoma patients on intraocular structures.Materials and Methods:One hundred-twenty six female glaucoma patients, who received mirabegron treatment for OAB symptoms between January 2017 and Jan...

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Main Authors: Emine Şeker Ün, Sıtkı Ün
Format: Article
Language:English
Published: Galenos Yayinevi 2020-06-01
Series:Journal of Urological Surgery
Subjects:
Online Access: http://jurolsurgery.org/archives/archive-detail/article-preview/effect-of-mirabegron-on-ntraocular-pressure-in-pat/38524
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author Emine Şeker Ün
Sıtkı Ün
author_facet Emine Şeker Ün
Sıtkı Ün
author_sort Emine Şeker Ün
collection DOAJ
description Objective:Assessment of the effects of mirabegron treatment used for overactive bladder (OAB) symptoms in glaucoma patients on intraocular structures.Materials and Methods:One hundred-twenty six female glaucoma patients, who received mirabegron treatment for OAB symptoms between January 2017 and January 2018, were included in the study. One hundred-twenty female glaucoma patients were chosen as controls. The mean age of the patients in the study and control groups was 46.74 and 44.42, respectively. A daily single dose of 50 mg mirabegron was prescribed for OAB treatment. Intraocular pressure (IOP) was assessed in 4th and 12th weeks in both groups. In the beginning of the treatment period, the mean IOP was 15.20 (±3.20) mmHg in the study group and 15.70 (±4.20) mmHg in controls.Results:The mean IOP in the study group was 15.80 (±3.80) mmHg and 16 (±4.20) mmHg on the 4th and 12th weeks, respectively. The mean IOP controls was 15.60 (±4.80) and 15.80 (±3.20) mmHg on the 4th and 12th weeks, respectively. No significant difference was found on the 4th and 12th weeks of treatment between the groups in terms of intraocular pressure.Conclusion:Mirabegron treatment used for OAB does not affect IOP in patients treated for primary open-angle glaucoma.
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spelling doaj.art-34e02eb15acf41068c3639ae1d2260fd2023-02-15T16:16:13ZengGalenos YayineviJournal of Urological Surgery2148-95802148-95802020-06-017213413810.4274/jus.galenos.2019.313513049054Effect of Mirabegron on Intraocular Pressure in Patients with GlaucomaEmine Şeker Ün0Sıtkı Ün1 Pamukkale University Faculty of Medicine, Department of Ophthalmology, Denizli, Turkiye Pamukkale University Faculty of Medicine, Department of Urology, Denizli, Turkiye Objective:Assessment of the effects of mirabegron treatment used for overactive bladder (OAB) symptoms in glaucoma patients on intraocular structures.Materials and Methods:One hundred-twenty six female glaucoma patients, who received mirabegron treatment for OAB symptoms between January 2017 and January 2018, were included in the study. One hundred-twenty female glaucoma patients were chosen as controls. The mean age of the patients in the study and control groups was 46.74 and 44.42, respectively. A daily single dose of 50 mg mirabegron was prescribed for OAB treatment. Intraocular pressure (IOP) was assessed in 4th and 12th weeks in both groups. In the beginning of the treatment period, the mean IOP was 15.20 (±3.20) mmHg in the study group and 15.70 (±4.20) mmHg in controls.Results:The mean IOP in the study group was 15.80 (±3.80) mmHg and 16 (±4.20) mmHg on the 4th and 12th weeks, respectively. The mean IOP controls was 15.60 (±4.80) and 15.80 (±3.20) mmHg on the 4th and 12th weeks, respectively. No significant difference was found on the 4th and 12th weeks of treatment between the groups in terms of intraocular pressure.Conclusion:Mirabegron treatment used for OAB does not affect IOP in patients treated for primary open-angle glaucoma. http://jurolsurgery.org/archives/archive-detail/article-preview/effect-of-mirabegron-on-ntraocular-pressure-in-pat/38524 mirabegronglaucomaoveractive bladder
spellingShingle Emine Şeker Ün
Sıtkı Ün
Effect of Mirabegron on Intraocular Pressure in Patients with Glaucoma
Journal of Urological Surgery
mirabegron
glaucoma
overactive bladder
title Effect of Mirabegron on Intraocular Pressure in Patients with Glaucoma
title_full Effect of Mirabegron on Intraocular Pressure in Patients with Glaucoma
title_fullStr Effect of Mirabegron on Intraocular Pressure in Patients with Glaucoma
title_full_unstemmed Effect of Mirabegron on Intraocular Pressure in Patients with Glaucoma
title_short Effect of Mirabegron on Intraocular Pressure in Patients with Glaucoma
title_sort effect of mirabegron on intraocular pressure in patients with glaucoma
topic mirabegron
glaucoma
overactive bladder
url http://jurolsurgery.org/archives/archive-detail/article-preview/effect-of-mirabegron-on-ntraocular-pressure-in-pat/38524
work_keys_str_mv AT eminesekerun effectofmirabegrononintraocularpressureinpatientswithglaucoma
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