Development of Membrane-Bound GM-CSF and IL-18 as an Effective Tumor Vaccine.

Development of Membrane-Bound GM-CSF and IL-18 as an Effective Tumor Vaccine.

The development of effective adjuvant is the key factor to boost the immunogenicity of tumor cells as a tumor vaccine. In this study, we expressed membrane-bound granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-18 (IL-18) as adjuvants in tumor cells to stimulate immune respo...

Full description

Bibliographic Details
Main Authors:	Chien-Chiao Huang, Kung-Kai Kuo, Ta-Chun Cheng, Chih-Hung Chuang, Chien-Han Kao, Yuan-Chin Hsieh, Kuang-Hung Cheng, Jaw-Yuan Wang, Chiu-Min Cheng, Chien-Shu Chen, Tian-Lu Cheng
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4506079?pdf=render

Similar Items

Functional production of a soluble and secreted single-chain antibody by a bacterial secretion system.
by: Chiu-Min Cheng, et al.
Published: (2014-01-01)

ERCC1 Overexpression Increases Radioresistance in Colorectal Cancer Cells
by: Yi-Jung Huang, et al.
Published: (2022-09-01)

Recombinant GM-CSF for diseases of GM-CSF insufficiency: Correcting dysfunctional mononuclear phagocyte disorders
by: Hillard M. Lazarus, et al.
Published: (2023-01-01)

G‐CSF/GM‐CSF‐induced hematopoietic dysregulation in the progression of solid tumors
by: Kai He, et al.
Published: (2022-07-01)

“Same same” but different? Exploring the impact of perceived organizational support at the school and teacher levels on teachers’ job engagement and organizational citizenship behavior
by: Chuan-Chung Hsieh, et al.
Published: (2022-12-01)

A Secondary Antibody-Detecting Molecular Weight Marker with Mouse and Rabbit IgG Fc Linear Epitopes for Western Blot Analysis.
by: Wen-Wei Lin, et al.
Published: (2016-01-01)

Immune Evasion of G-CSF and GM-CSF in Lung Cancer
by: Yeonhee Park, et al.
Published: (2024-01-01)

Efficient Human Action and Gait Analysis Using Multiresolution Motion Energy Histogram
by: Cheng Hsu-Yung, et al.
Published: (2010-01-01)

Efficient Human Action and Gait Analysis Using Multiresolution Motion Energy Histogram
by: Kuo-Chin Fan, et al.
Published: (2010-01-01)

GM-CSF signalling boosts dramatically IL-1 production.
by: Hanif Javanmard Khameneh, et al.
Published: (2011-01-01)

GM-CSF-Dependent Inflammatory Pathways
by: John A. Hamilton, et al.
Published: (2019-09-01)

Real-Time Object Localization Using a Fuzzy Controller for a Vision-Based Drone
by: Ping-Sheng Wang, et al.
Published: (2024-01-01)

Literary Reading by Virtual Reality: The Role of Empathy in Behavioral Intention and Reading Comprehension
by: Yun-Chien Chuang, et al.
Published: (2023-03-01)

The characteristics of residents with unawareness of hepatitis C virus infection in community.
by: Pin-Nan Cheng, et al.
Published: (2018-01-01)

Real-world effectiveness and safety of sofosbuvir plus daclatasvir with or without ribavirin for genotype 2 chronic hepatitis C in Taiwan
by: Pin-Nan Cheng, et al.
Published: (2019-05-01)

IL-12 and IL-18 require IFN-gamma and GM-CSF signaling, and are essential for normal bone remodeling and bone mass.
by: Sims, N, et al.
Published: (2005)

Response to treatment with TNFα inhibitors in rheumatoid arthritis is associated with high levels of GM-CSF and GM-CSF(+) T lymphocytes
by: Bystrom, J, et al.
Published: (2017)

Construction of Recombinant Human GM-CSF and GM-CSF-ApoA-I Fusion Protein and Evaluation of Their Biological Activity
by: Mariya Pykhtina, et al.
Published: (2021-05-01)

Optimal Configuration with Capacity Analysis of PV-Plus-BESS for Behind-the-Meter Application
by: Cheng-Yu Peng, et al.
Published: (2021-08-01)

Role of GM-CSF in lung balance and disease
by: Yingzi Chen, et al.
Published: (2023-04-01)

M-CSF and GM-CSF determinate fibromodulatory activity of polarized human macrophages
by: A. A. Maksimova, et al.
Published: (2022-11-01)

Correction to: Cellular immunotherapy using irradiated lung cancer cell vaccine co-expressing GM-CSF and IL-18 can induce significant antitumor effects
by: Hongwei Tian, et al.
Published: (2020-01-01)

A Retrospective Administrative Database Analysis of Suicide Attempts and Completed Suicide in Patients With Chronic Pancreatitis
by: Chien-Hua Chen, et al.
Published: (2018-04-01)

Association Between Type I and II Diabetes With Gallbladder Stone Disease
by: Chien-Hua Chen, et al.
Published: (2018-11-01)

Chronic Hepatitis C Virus Infection: An Ongoing Challenge in Screening and Treatment
by: Wei-Chu Tsai, et al.
Published: (2023-09-01)

Real-time imaging of intestinal bacterial β-glucuronidase activity by hydrolysis of a fluorescent probe
by: Michael Chen, et al.
Published: (2017-06-01)

HIV Replication in Humanized IL-3/GM-CSF-Transgenic NOG Mice
by: Federico Perdomo-Celis, et al.
Published: (2019-03-01)

The Effect of Post-Graduate Year Training on the Self-Efficacy and Emotional Traits of Physicians Facing the COVID-19 Pandemic
by: Chih-Hung Chen, et al.
Published: (2021-07-01)

Research Upregulation of CD23 (FcεRII) Expression in Human Airway Smooth Muscle Cells (huASMC) in Response to IL-4, GM-CSF, and IL-4/GM-CSF
by: Lew D Betty, et al.
Published: (2005-05-01)

High-throughput sorting of the highest producing cell via a transiently protein-anchored system.
by: Kuo-Hsiang Chuang, et al.
Published: (2014-01-01)

Germanium diffusion with vapor-phase GeAs and oxygen co-incorporation in GaAs
by: Wei-Fu Wang, et al.
Published: (2018-01-01)

RETRACTED ARTICLE: Cellular immunotherapy using irradiated lung cancer cell vaccine co-expressing GM-CSF and IL-18 can induce significant antitumor effects
by: Hongwei Tian, et al.
Published: (2014-01-01)

Retraction Note: Cellular immunotherapy using irradiated lung cancer cell vaccine co-expressing GM-CSF and IL-18 can induce significant antitumor effects
by: Hongwei Tian, et al.
Published: (2023-07-01)

Hyperbaric Oxygen Therapy Alleviates the Autoimmune Encephalomyelitis via the Reduction of IL-17a and GM-Csf Production of Autoreactive T Cells as Well as Boosting the Immunosuppressive IL-10 in the Central Nervous System Tissue Lesions
by: Hsin-Ying Clair Chiou, et al.
Published: (2021-08-01)

GM-CSF: A Promising Target in Inflammation and Autoimmunity
by: Lee KMC, et al.
Published: (2020-10-01)

Functional characterization of GM-CSF induced monocyte subsets
by: Däbritz J, et al.
Published: (2008-09-01)

Osteogenic differentiation of placenta-derived multipotent cells in vitro
by: Chih-Chien Cheng, et al.
Published: (2014-06-01)

Robot-assisted restorative proctectomy with coloanal anastomosis for anorectal malignant melanoma: An unusual case report
by: Yi-Chien Hsieh, et al.
Published: (2020-01-01)

Characterization of the function and expression of the murine granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor with a novel GM-CSF fusion protein
by: Rosas, M, et al.
Published: (2005)

GM-CSF Dependent Differential Control of Mycobacterium tuberculosis Infection in Human and Mouse Macrophages: Is Macrophage Source of GM-CSF Critical to Tuberculosis Immunity?
by: Abhishek Mishra, et al.
Published: (2020-07-01)