Glycemic index, glycemic load, dietary inflammatory index, and risk of infertility in women
Abstract The dietary glycemic load (GL) indicates the quantity and quality of carbohydrates, which can affect ovulation and fertility by controlling insulin sensitivity. Also, past studies confirm the role of the dietary inflammatory index (DII) in many diseases, including metabolic syndrome and car...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-10-01
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| Series: | Food Science & Nutrition |
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| Online Access: | https://doi.org/10.1002/fsn3.3584 |
| _version_ | 1797662504345665536 |
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| author | Behnaz Aghaei Fardin Moradi Davood Soleimani Mehdi Moradinazar Tina Khosravy Mehnoosh Samadi |
| author_facet | Behnaz Aghaei Fardin Moradi Davood Soleimani Mehdi Moradinazar Tina Khosravy Mehnoosh Samadi |
| author_sort | Behnaz Aghaei |
| collection | DOAJ |
| description | Abstract The dietary glycemic load (GL) indicates the quantity and quality of carbohydrates, which can affect ovulation and fertility by controlling insulin sensitivity. Also, past studies confirm the role of the dietary inflammatory index (DII) in many diseases, including metabolic syndrome and cardiovascular disorders, so it may be related to reproductive health. This case–control study aims to study the association between glycemic index (GI), GL, and DII with infertility in women. This study was conducted on 300 infertile women in the case group and 300 fertile women in the control group in Kermanshah, Iran. Food intake was evaluated using FFQ, and using NUTRITIONIST IV software programs, GI and GL values were determined. DII was computed as well using FFQ data. Physical activity was assessed using IPAQ‐SF. The association between GI, GL, and DII with infertility was evaluated using a logistic regression test, using STATA version 14 software. The results showed that the DII, GI, and GL were higher in the case group compared to the control group ([p = .009], [p = .0001], and [p = .0007], respectively). The increase in GI, GL, and DII caused an increase in infertility factors, and consequently enhanced chance of infertility ((adjusted odd ratio [OR] 2; 95% confidence interval [CI], 1.16, 3.45), (OR 3.68; 95% CI, 1.99, 6.82), and (OR 1.7; 95% CI, 0.97, 2.95), respectively). The present study indicated that the chance of infertility is higher in women who follow a diet with high GI, GL, and DII. Therefore, a positive association may be present between GI, GL, and DII with infertility. |
| first_indexed | 2024-03-11T19:00:12Z |
| format | Article |
| id | doaj.art-34e1f5faca764937940722927f8da05f |
| institution | Directory Open Access Journal |
| issn | 2048-7177 |
| language | English |
| last_indexed | 2024-03-11T19:00:12Z |
| publishDate | 2023-10-01 |
| publisher | Wiley |
| record_format | Article |
| series | Food Science & Nutrition |
| spelling | doaj.art-34e1f5faca764937940722927f8da05f2023-10-10T12:30:22ZengWileyFood Science & Nutrition2048-71772023-10-0111106413642410.1002/fsn3.3584Glycemic index, glycemic load, dietary inflammatory index, and risk of infertility in womenBehnaz Aghaei0Fardin Moradi1Davood Soleimani2Mehdi Moradinazar3Tina Khosravy4Mehnoosh Samadi5Student Research Committee, Department of Nutritional Sciences, School of Nutrition Sciences and Food Technology Kermanshah University of Medical Sciences Kermanshah IranStudent Research Committee, Department of Nutritional Sciences, School of Nutrition Sciences and Food Technology Kermanshah University of Medical Sciences Kermanshah IranStudent Research Committee, Department of Nutritional Sciences, School of Nutrition Sciences and Food Technology Kermanshah University of Medical Sciences Kermanshah IranBehavioral Disease Research Center Kermanshah University of Medical Sciences Kermanshah IranDepartment of Health Nutrition Lorestan University of Medical Sciences Khorramabad IranStudent Research Committee, Department of Nutritional Sciences, School of Nutrition Sciences and Food Technology Kermanshah University of Medical Sciences Kermanshah IranAbstract The dietary glycemic load (GL) indicates the quantity and quality of carbohydrates, which can affect ovulation and fertility by controlling insulin sensitivity. Also, past studies confirm the role of the dietary inflammatory index (DII) in many diseases, including metabolic syndrome and cardiovascular disorders, so it may be related to reproductive health. This case–control study aims to study the association between glycemic index (GI), GL, and DII with infertility in women. This study was conducted on 300 infertile women in the case group and 300 fertile women in the control group in Kermanshah, Iran. Food intake was evaluated using FFQ, and using NUTRITIONIST IV software programs, GI and GL values were determined. DII was computed as well using FFQ data. Physical activity was assessed using IPAQ‐SF. The association between GI, GL, and DII with infertility was evaluated using a logistic regression test, using STATA version 14 software. The results showed that the DII, GI, and GL were higher in the case group compared to the control group ([p = .009], [p = .0001], and [p = .0007], respectively). The increase in GI, GL, and DII caused an increase in infertility factors, and consequently enhanced chance of infertility ((adjusted odd ratio [OR] 2; 95% confidence interval [CI], 1.16, 3.45), (OR 3.68; 95% CI, 1.99, 6.82), and (OR 1.7; 95% CI, 0.97, 2.95), respectively). The present study indicated that the chance of infertility is higher in women who follow a diet with high GI, GL, and DII. Therefore, a positive association may be present between GI, GL, and DII with infertility.https://doi.org/10.1002/fsn3.3584dietary inflammatory index (DII)glycemic indexglycemic loadinfertilityinflammation |
| spellingShingle | Behnaz Aghaei Fardin Moradi Davood Soleimani Mehdi Moradinazar Tina Khosravy Mehnoosh Samadi Glycemic index, glycemic load, dietary inflammatory index, and risk of infertility in women Food Science & Nutrition dietary inflammatory index (DII) glycemic index glycemic load infertility inflammation |
| title | Glycemic index, glycemic load, dietary inflammatory index, and risk of infertility in women |
| title_full | Glycemic index, glycemic load, dietary inflammatory index, and risk of infertility in women |
| title_fullStr | Glycemic index, glycemic load, dietary inflammatory index, and risk of infertility in women |
| title_full_unstemmed | Glycemic index, glycemic load, dietary inflammatory index, and risk of infertility in women |
| title_short | Glycemic index, glycemic load, dietary inflammatory index, and risk of infertility in women |
| title_sort | glycemic index glycemic load dietary inflammatory index and risk of infertility in women |
| topic | dietary inflammatory index (DII) glycemic index glycemic load infertility inflammation |
| url | https://doi.org/10.1002/fsn3.3584 |
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