Scutellaria baicalensis Georgi stems and leaves flavonoids promote neuroregeneration and ameliorate memory loss in rats through cAMP-PKA-CREB signaling pathway based on network pharmacology and bioinformatics analysis

Scutellaria baicalensis Georgi stems and leaves flavonoids promote neuroregeneration and ameliorate memory loss in rats through cAMP-PKA-CREB signaling pathway based on network pharmacology and bioinformatics analysis

The aim of this study was to investigate the possible molecular mechanism of Scutellaria baicalensis Georgi stems and leaves flavonoids (SSF) in Alzheimer's disease (AD). The active ingredients of SSF and their targets were identified via network pharmacology and bioinformatics analysis. To tes...

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Bibliographic Details
Main Authors: Yinhui Yao, Qianqian Liu, Shengkai Ding, Yan Chen, Tangtang Song, Yazhen Shang
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Heliyon
Subjects:
Scutellaria baicalensis georgi
Flavonoids
Stems and leaves
cAMP-PKA-CREB signaling pathway
Alzheimer's disease
Bioinformatics
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402403192X

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