Scientific Opinion on the safety and efficacy of <em>Lactobacillus acidophilus</em> D2/CSL (<em>Lactobacillus acidophilus</em>) for laying hens
Lactobacillus acidophilus D2/CSL is the trade name for a preparation of a strain of Lactobacillus acidophilus. EFSA was requested to re-evaluate the additive when used in feed for laying hens at a minimum dose of 1 × 109 CFU/kg feed and to assess the safety and efficacy of its use in water for drink...
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| Format: | Article |
| Language: | English |
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Wiley
2014-07-01
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| Series: | EFSA Journal |
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| Online Access: | http://www.efsa.europa.eu/en/efsajournal/doc/3789.pdf |
| _version_ | 1818730471942520832 |
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| author | EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) |
| author_facet | EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) |
| author_sort | EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) |
| collection | DOAJ |
| description | Lactobacillus acidophilus D2/CSL is the trade name for a preparation of a strain of Lactobacillus acidophilus. EFSA was requested to re-evaluate the additive when used in feed for laying hens at a minimum dose of 1 × 109 CFU/kg feed and to assess the safety and efficacy of its use in water for drinking for the same species. The identity of L. acidophilus has been established and no resistance to clinically relevant antibiotics has been detected. The strain satisfies the requirements for the qualified presumption of safety approach to safety assessment and, thus, is presumed safe for the target animals, consumers of products derived from animals fed the additive, and the environment. The additive should be considered to be an eye/skin irritant and a skin/respiratory sensitiser and treated accordingly. On the basis of three studies performed with laying hens, the FEEDAP Panel concludes that Lactobacillus acidophilus D2/CSL has the potential to increase laying intensity and significantly improve the feed-to-egg mass ratio at the proposed dose of 1 × 109 CFU/kg feed. The FEEDAP Panel considers that the results are independent of the mode of administration, provided that exposure is the same and that the equivalent dose in water for drinking would be 3–5 × 108 CFU/L. |
| first_indexed | 2024-12-17T23:02:19Z |
| format | Article |
| id | doaj.art-34f99d16bc434741811270dc371f0dbe |
| institution | Directory Open Access Journal |
| issn | 1831-4732 |
| language | English |
| last_indexed | 2024-12-17T23:02:19Z |
| publishDate | 2014-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | EFSA Journal |
| spelling | doaj.art-34f99d16bc434741811270dc371f0dbe2022-12-21T21:29:23ZengWileyEFSA Journal1831-47322014-07-0112710.2903/j.efsa.2014.3789EFSA Journal 2014;12(7):3789Scientific Opinion on the safety and efficacy of <em>Lactobacillus acidophilus</em> D2/CSL (<em>Lactobacillus acidophilus</em>) for laying hensEFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)Lactobacillus acidophilus D2/CSL is the trade name for a preparation of a strain of Lactobacillus acidophilus. EFSA was requested to re-evaluate the additive when used in feed for laying hens at a minimum dose of 1 × 109 CFU/kg feed and to assess the safety and efficacy of its use in water for drinking for the same species. The identity of L. acidophilus has been established and no resistance to clinically relevant antibiotics has been detected. The strain satisfies the requirements for the qualified presumption of safety approach to safety assessment and, thus, is presumed safe for the target animals, consumers of products derived from animals fed the additive, and the environment. The additive should be considered to be an eye/skin irritant and a skin/respiratory sensitiser and treated accordingly. On the basis of three studies performed with laying hens, the FEEDAP Panel concludes that Lactobacillus acidophilus D2/CSL has the potential to increase laying intensity and significantly improve the feed-to-egg mass ratio at the proposed dose of 1 × 109 CFU/kg feed. The FEEDAP Panel considers that the results are independent of the mode of administration, provided that exposure is the same and that the equivalent dose in water for drinking would be 3–5 × 108 CFU/L.http://www.efsa.europa.eu/en/efsajournal/doc/3789.pdfzootechnical additiveLactobacillus acidophilus D2/CSLlaying hensefficacysafetyQPS |
| spellingShingle | EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) Scientific Opinion on the safety and efficacy of <em>Lactobacillus acidophilus</em> D2/CSL (<em>Lactobacillus acidophilus</em>) for laying hens EFSA Journal zootechnical additive Lactobacillus acidophilus D2/CSL laying hens efficacy safety QPS |
| title | Scientific Opinion on the safety and efficacy of <em>Lactobacillus acidophilus</em> D2/CSL (<em>Lactobacillus acidophilus</em>) for laying hens |
| title_full | Scientific Opinion on the safety and efficacy of <em>Lactobacillus acidophilus</em> D2/CSL (<em>Lactobacillus acidophilus</em>) for laying hens |
| title_fullStr | Scientific Opinion on the safety and efficacy of <em>Lactobacillus acidophilus</em> D2/CSL (<em>Lactobacillus acidophilus</em>) for laying hens |
| title_full_unstemmed | Scientific Opinion on the safety and efficacy of <em>Lactobacillus acidophilus</em> D2/CSL (<em>Lactobacillus acidophilus</em>) for laying hens |
| title_short | Scientific Opinion on the safety and efficacy of <em>Lactobacillus acidophilus</em> D2/CSL (<em>Lactobacillus acidophilus</em>) for laying hens |
| title_sort | scientific opinion on the safety and efficacy of em lactobacillus acidophilus em d2 csl em lactobacillus acidophilus em for laying hens |
| topic | zootechnical additive Lactobacillus acidophilus D2/CSL laying hens efficacy safety QPS |
| url | http://www.efsa.europa.eu/en/efsajournal/doc/3789.pdf |
| work_keys_str_mv | AT efsapanelonadditivesandproductsorsubstancesusedinanimalfeedfeedap scientificopiniononthesafetyandefficacyofemlactobacillusacidophilusemd2cslemlactobacillusacidophilusemforlayinghens |