Thimet Oligopeptidase Biochemical and Biological Significances: Past, Present, and Future Directions

Thimet Oligopeptidase Biochemical and Biological Significances: Past, Present, and Future Directions

Thimet oligopeptidase (EC 3.4.24.15; EP24.15, THOP1) is a metallopeptidase ubiquitously distributed in mammalian tissues. Beyond its previously well characterized role in major histocompatibility class I (MHC-I) antigen presentation, the recent characterization of the THOP1 C57BL6/N null mice (THOP1...

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Bibliographic Details
Main Authors:	Emer S. Ferro, Mayara C. F. Gewehr, Ami Navon
Format:	Article
Language:	English
Published:	MDPI AG 2020-08-01
Series:	Biomolecules
Subjects:	peptide metabolism peptidase protease proteasome protein-protein interaction microRNA
Online Access:	https://www.mdpi.com/2218-273X/10/9/1229

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