Melanopsin (Opn4) is an oncogene in cutaneous melanoma
Melanopsin (Opn4) is identified as an oncogene in cutaneous melanoma, with the loss of Opn4 found to be associated with reduced proliferation and tumor growth, due to changes in immune responses and Mitf signaling in vitro and in vivo.
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-05-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-03425-6 |
| _version_ | 1818005846975578112 |
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| author | Leonardo Vinícius Monteiro de Assis José Thalles Lacerda Maria Nathália Moraes Omar Alberto Domínguez-Amorocho Gabriela Sarti Kinker Davi Mendes Matheus Molina Silva Carlos Frederico Martins Menck Niels Olsen Saraiva Câmara Ana Maria de Lauro Castrucci |
| author_facet | Leonardo Vinícius Monteiro de Assis José Thalles Lacerda Maria Nathália Moraes Omar Alberto Domínguez-Amorocho Gabriela Sarti Kinker Davi Mendes Matheus Molina Silva Carlos Frederico Martins Menck Niels Olsen Saraiva Câmara Ana Maria de Lauro Castrucci |
| author_sort | Leonardo Vinícius Monteiro de Assis |
| collection | DOAJ |
| description | Melanopsin (Opn4) is identified as an oncogene in cutaneous melanoma, with the loss of Opn4 found to be associated with reduced proliferation and tumor growth, due to changes in immune responses and Mitf signaling in vitro and in vivo. |
| first_indexed | 2024-04-14T04:50:54Z |
| format | Article |
| id | doaj.art-34ff8296efc64f529ce55ec839ae4b5e |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-14T04:50:54Z |
| publishDate | 2022-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-34ff8296efc64f529ce55ec839ae4b5e2022-12-22T02:11:17ZengNature PortfolioCommunications Biology2399-36422022-05-015111510.1038/s42003-022-03425-6Melanopsin (Opn4) is an oncogene in cutaneous melanomaLeonardo Vinícius Monteiro de Assis0José Thalles Lacerda1Maria Nathália Moraes2Omar Alberto Domínguez-Amorocho3Gabriela Sarti Kinker4Davi Mendes5Matheus Molina Silva6Carlos Frederico Martins Menck7Niels Olsen Saraiva Câmara8Ana Maria de Lauro Castrucci9Laboratory of Comparative Physiology of Pigmentation, Department of Physiology, Institute of Biosciences, University of São PauloLaboratory of Comparative Physiology of Pigmentation, Department of Physiology, Institute of Biosciences, University of São PauloLaboratory of Neurobiology, Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of São PauloLaboratory of Transplantation Immunobiology, Institute of Biomedical Sciences, University of São PauloLaboratory of Translational Immuno-Oncology A. C. Camargo Cancer Center – International Research CenterDNA Repair Lab, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo (USP)DNA Repair Lab, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo (USP)DNA Repair Lab, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo (USP)Laboratory of Transplantation Immunobiology, Institute of Biomedical Sciences, University of São PauloLaboratory of Comparative Physiology of Pigmentation, Department of Physiology, Institute of Biosciences, University of São PauloMelanopsin (Opn4) is identified as an oncogene in cutaneous melanoma, with the loss of Opn4 found to be associated with reduced proliferation and tumor growth, due to changes in immune responses and Mitf signaling in vitro and in vivo.https://doi.org/10.1038/s42003-022-03425-6 |
| spellingShingle | Leonardo Vinícius Monteiro de Assis José Thalles Lacerda Maria Nathália Moraes Omar Alberto Domínguez-Amorocho Gabriela Sarti Kinker Davi Mendes Matheus Molina Silva Carlos Frederico Martins Menck Niels Olsen Saraiva Câmara Ana Maria de Lauro Castrucci Melanopsin (Opn4) is an oncogene in cutaneous melanoma Communications Biology |
| title | Melanopsin (Opn4) is an oncogene in cutaneous melanoma |
| title_full | Melanopsin (Opn4) is an oncogene in cutaneous melanoma |
| title_fullStr | Melanopsin (Opn4) is an oncogene in cutaneous melanoma |
| title_full_unstemmed | Melanopsin (Opn4) is an oncogene in cutaneous melanoma |
| title_short | Melanopsin (Opn4) is an oncogene in cutaneous melanoma |
| title_sort | melanopsin opn4 is an oncogene in cutaneous melanoma |
| url | https://doi.org/10.1038/s42003-022-03425-6 |
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