USP9X-mediated NRP1 deubiquitination promotes liver fibrosis by activating hepatic stellate cells

Abstract Liver fibrosis is a complex fibrotic process that develops early in the course of cirrhosis and is caused by chronic liver damage. The activation of hepatic stellate cells is primarily responsible for the fibrosis process. Studies show that NRP1 influences HSC motility and migration. Howeve...

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Bibliographic Details
Main Authors: Jinqiu Zhao, Jie Bai, Fengling Peng, Chan Qiu, Yongguo Li, Li Zhong
Format: Article
Language:English
Published: Nature Publishing Group 2023-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05527-9

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