Acupuncture for Improving Cognitive Impairment After Stroke: A Meta-Analysis of Randomized Controlled Trials
Objective: This meta-analysis evaluated the efficacy of acupuncture in improving cognitive impairment of post-stroke patients.Design: Randomized controlled trials (RCTs) investigating the effects of acupuncture compared with no treatment or sham acupuncture on post-stroke cognitive impairment (PSCI)...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-11-01
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| Series: | Frontiers in Psychology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyg.2020.549265/full |
| _version_ | 1819072791754833920 |
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| author | Liang Zhou Yao Wang Jun Qiao Qing Mei Wang Xun Luo Xun Luo |
| author_facet | Liang Zhou Yao Wang Jun Qiao Qing Mei Wang Xun Luo Xun Luo |
| author_sort | Liang Zhou |
| collection | DOAJ |
| description | Objective: This meta-analysis evaluated the efficacy of acupuncture in improving cognitive impairment of post-stroke patients.Design: Randomized controlled trials (RCTs) investigating the effects of acupuncture compared with no treatment or sham acupuncture on post-stroke cognitive impairment (PSCI) before December 2019 were identified from databases (PubMed, EMBASE, Ovid library, Cochrane Library, Chinese National Knowledge Infrastructure, VIP Chinese Periodical Database, Wanfang Database, and SinoMed). The literature searching and data extracting were independently performed by two investigators. Study quality was assessed using the Cochrane Handbook for Systematic Reviews of Interventions. Meta-analyses were performed for the eligible RCTs with Revman 5.3 software.Results: Thirty-seven RCTs (2,869 patients) were included in this meta-analysis. Merged Random-effects estimates of the gain of MMSE (Mini-Mental State Examination) or MoCA (Montreal Cognitive Assessment) were calculated for the comparison of acupuncture with no acupuncture or sham acupuncture. Following 2–8 weeks of intervention with acupuncture, pooled results demonstrated significant effects of acupuncture in improving PSCI assessed by MMSE (MD [95% CI] = 2.88 [2.09, 3.66], p < 0.00001) or MoCA (MD [95% CI] = 2.66 [1.95, 3.37], p < 0.00001).Conclusion: The results suggest that acupuncture was effective in improving PSCI and supported the needs of more rigorous design with large-scale randomized clinical trials to determine its therapeutic benefits. |
| first_indexed | 2024-12-21T17:43:21Z |
| format | Article |
| id | doaj.art-34ff9265e9b34c9e8204d9d3ee9883f8 |
| institution | Directory Open Access Journal |
| issn | 1664-1078 |
| language | English |
| last_indexed | 2024-12-21T17:43:21Z |
| publishDate | 2020-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychology |
| spelling | doaj.art-34ff9265e9b34c9e8204d9d3ee9883f82022-12-21T18:55:34ZengFrontiers Media S.A.Frontiers in Psychology1664-10782020-11-011110.3389/fpsyg.2020.549265549265Acupuncture for Improving Cognitive Impairment After Stroke: A Meta-Analysis of Randomized Controlled TrialsLiang Zhou0Yao Wang1Jun Qiao2Qing Mei Wang3Xun Luo4Xun Luo5Department of Reproductive Medicine, Peking University Shenzhen Hospital, Shenzhen, ChinaDepartment of Rehabilitation Medicine, Dapeng New District Nan'ao People's Hospital, Shenzhen, ChinaThe Second Rehabilitation Hospital of Shanghai, Shanghai, ChinaStroke Biological Recovery Laboratory, Spaulding Rehabilitation Hospital, The Teaching Affiliate of Harvard Medical School, Boston, MA, United StatesDepartment of Rehabilitation Medicine, Dapeng New District Nan'ao People's Hospital, Shenzhen, ChinaKerry Rehabilitation Medicine Research Institute, Shenzhen, ChinaObjective: This meta-analysis evaluated the efficacy of acupuncture in improving cognitive impairment of post-stroke patients.Design: Randomized controlled trials (RCTs) investigating the effects of acupuncture compared with no treatment or sham acupuncture on post-stroke cognitive impairment (PSCI) before December 2019 were identified from databases (PubMed, EMBASE, Ovid library, Cochrane Library, Chinese National Knowledge Infrastructure, VIP Chinese Periodical Database, Wanfang Database, and SinoMed). The literature searching and data extracting were independently performed by two investigators. Study quality was assessed using the Cochrane Handbook for Systematic Reviews of Interventions. Meta-analyses were performed for the eligible RCTs with Revman 5.3 software.Results: Thirty-seven RCTs (2,869 patients) were included in this meta-analysis. Merged Random-effects estimates of the gain of MMSE (Mini-Mental State Examination) or MoCA (Montreal Cognitive Assessment) were calculated for the comparison of acupuncture with no acupuncture or sham acupuncture. Following 2–8 weeks of intervention with acupuncture, pooled results demonstrated significant effects of acupuncture in improving PSCI assessed by MMSE (MD [95% CI] = 2.88 [2.09, 3.66], p < 0.00001) or MoCA (MD [95% CI] = 2.66 [1.95, 3.37], p < 0.00001).Conclusion: The results suggest that acupuncture was effective in improving PSCI and supported the needs of more rigorous design with large-scale randomized clinical trials to determine its therapeutic benefits.https://www.frontiersin.org/articles/10.3389/fpsyg.2020.549265/fullMMSEcognitive impairmentelectroacupunctureacupuncturepost stroke |
| spellingShingle | Liang Zhou Yao Wang Jun Qiao Qing Mei Wang Xun Luo Xun Luo Acupuncture for Improving Cognitive Impairment After Stroke: A Meta-Analysis of Randomized Controlled Trials Frontiers in Psychology MMSE cognitive impairment electroacupuncture acupuncture post stroke |
| title | Acupuncture for Improving Cognitive Impairment After Stroke: A Meta-Analysis of Randomized Controlled Trials |
| title_full | Acupuncture for Improving Cognitive Impairment After Stroke: A Meta-Analysis of Randomized Controlled Trials |
| title_fullStr | Acupuncture for Improving Cognitive Impairment After Stroke: A Meta-Analysis of Randomized Controlled Trials |
| title_full_unstemmed | Acupuncture for Improving Cognitive Impairment After Stroke: A Meta-Analysis of Randomized Controlled Trials |
| title_short | Acupuncture for Improving Cognitive Impairment After Stroke: A Meta-Analysis of Randomized Controlled Trials |
| title_sort | acupuncture for improving cognitive impairment after stroke a meta analysis of randomized controlled trials |
| topic | MMSE cognitive impairment electroacupuncture acupuncture post stroke |
| url | https://www.frontiersin.org/articles/10.3389/fpsyg.2020.549265/full |
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