Nitrous Oxide sedation for intra-articular injection in juvenile idiopathic arthritis

<p>Abstract</p> <p>Background</p> <p>Intra-articular corticosteroid injection in juvenile idiopathic arthritis (JIA) is often associated with anxiety and pain. Recent reports advocate the use of nitrous oxide (NO), a volatile gas with analgesic, anxiolytic and sedative...

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Main Authors: Harel Liora, Press Joseph, Tauber Tsivia, Rothschild Michal, Chapnick Gil, Uziel Yosef, Hashkes Philip J
Format: Article
Language:English
Published: BMC 2008-01-01
Series:Pediatric Rheumatology Online Journal
Online Access:http://www.ped-rheum.com/content/6/1/1
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author Harel Liora
Press Joseph
Tauber Tsivia
Rothschild Michal
Chapnick Gil
Uziel Yosef
Hashkes Philip J
author_facet Harel Liora
Press Joseph
Tauber Tsivia
Rothschild Michal
Chapnick Gil
Uziel Yosef
Hashkes Philip J
author_sort Harel Liora
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Intra-articular corticosteroid injection in juvenile idiopathic arthritis (JIA) is often associated with anxiety and pain. Recent reports advocate the use of nitrous oxide (NO), a volatile gas with analgesic, anxiolytic and sedative properties.</p> <p>Objective</p> <p>To prospectively evaluate the effectiveness and safety of NO analgesia for intra-articular corticosteroid injection in JIA, and to assess patients and staff satisfaction with the treatment.</p> <p>Methods</p> <p>NO was administered to JIA patients scheduled for joint injection. The patient, parent, physician and nurse completed visual-analog scores (VAS) (0–10) for pain, and a 5-point satisfaction scale. Change in heart rate (HR) during the procedure was recorded in order to examine physiologic response to pain and stress. Patient's behavior and adverse reactions were recorded.</p> <p>Results</p> <p>54 procedures (72 joints) were performed, 41 females, 13 males; 39 Jewish, 13 Arab; mean age was 12.2 ± 4.7 year. The median VAS pain score for patients, parents, physicians and nurses was 3. The HR increased ≥ 15% in 10 patients. They had higher VAS scores as evaluated by the staff. The median satisfaction level of the parents and staff was 3.0 and 5.0 respectively. Adverse reactions were mild.</p> <p>Conclusion</p> <p>NO provides effective and safe sedation for JIA children undergoing intra-articular injections.</p>
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spelling doaj.art-34ffa7fcee8b47bbb5224a6f2333aef62022-12-22T03:18:40ZengBMCPediatric Rheumatology Online Journal1546-00962008-01-0161110.1186/1546-0096-6-1Nitrous Oxide sedation for intra-articular injection in juvenile idiopathic arthritisHarel LioraPress JosephTauber TsiviaRothschild MichalChapnick GilUziel YosefHashkes Philip J<p>Abstract</p> <p>Background</p> <p>Intra-articular corticosteroid injection in juvenile idiopathic arthritis (JIA) is often associated with anxiety and pain. Recent reports advocate the use of nitrous oxide (NO), a volatile gas with analgesic, anxiolytic and sedative properties.</p> <p>Objective</p> <p>To prospectively evaluate the effectiveness and safety of NO analgesia for intra-articular corticosteroid injection in JIA, and to assess patients and staff satisfaction with the treatment.</p> <p>Methods</p> <p>NO was administered to JIA patients scheduled for joint injection. The patient, parent, physician and nurse completed visual-analog scores (VAS) (0–10) for pain, and a 5-point satisfaction scale. Change in heart rate (HR) during the procedure was recorded in order to examine physiologic response to pain and stress. Patient's behavior and adverse reactions were recorded.</p> <p>Results</p> <p>54 procedures (72 joints) were performed, 41 females, 13 males; 39 Jewish, 13 Arab; mean age was 12.2 ± 4.7 year. The median VAS pain score for patients, parents, physicians and nurses was 3. The HR increased ≥ 15% in 10 patients. They had higher VAS scores as evaluated by the staff. The median satisfaction level of the parents and staff was 3.0 and 5.0 respectively. Adverse reactions were mild.</p> <p>Conclusion</p> <p>NO provides effective and safe sedation for JIA children undergoing intra-articular injections.</p>http://www.ped-rheum.com/content/6/1/1
spellingShingle Harel Liora
Press Joseph
Tauber Tsivia
Rothschild Michal
Chapnick Gil
Uziel Yosef
Hashkes Philip J
Nitrous Oxide sedation for intra-articular injection in juvenile idiopathic arthritis
Pediatric Rheumatology Online Journal
title Nitrous Oxide sedation for intra-articular injection in juvenile idiopathic arthritis
title_full Nitrous Oxide sedation for intra-articular injection in juvenile idiopathic arthritis
title_fullStr Nitrous Oxide sedation for intra-articular injection in juvenile idiopathic arthritis
title_full_unstemmed Nitrous Oxide sedation for intra-articular injection in juvenile idiopathic arthritis
title_short Nitrous Oxide sedation for intra-articular injection in juvenile idiopathic arthritis
title_sort nitrous oxide sedation for intra articular injection in juvenile idiopathic arthritis
url http://www.ped-rheum.com/content/6/1/1
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