Post-COVID syndrome: A prospective study in a tertiary hospital of Nepal.
<h4>Introduction</h4>The post-coronavirus disease 2019 (COVID-19) syndrome is defined as the persistence of symptoms after viral clearance and the emergence of new symptoms after a few months following recovery from COVID-19. This study aimed to assess the prevalence of post-COVID-19 syn...
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2022-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0272636 |
| _version_ | 1811302548084097024 |
|---|---|
| author | Sangam Shah Shreeyash Raj Bhattarai Kriti Basnet Yagya Raj Adhikari Tara Ballav Adhikari Nikita Bhatta Rajan Chamlagain Susan Aryal Sanjit Kumar Sah Govinda Bhandari Bibek Bhandari Sujan Poudel Pankaj Pant Santa Kumar Das |
| author_facet | Sangam Shah Shreeyash Raj Bhattarai Kriti Basnet Yagya Raj Adhikari Tara Ballav Adhikari Nikita Bhatta Rajan Chamlagain Susan Aryal Sanjit Kumar Sah Govinda Bhandari Bibek Bhandari Sujan Poudel Pankaj Pant Santa Kumar Das |
| author_sort | Sangam Shah |
| collection | DOAJ |
| description | <h4>Introduction</h4>The post-coronavirus disease 2019 (COVID-19) syndrome is defined as the persistence of symptoms after viral clearance and the emergence of new symptoms after a few months following recovery from COVID-19. This study aimed to assess the prevalence of post-COVID-19 syndrome and the risk factors that contribute to its development.<h4>Methods</h4>This study was conducted prospectively in Tribhuvan University Teaching Hospital (TUTH), located in Maharajgunj, Kathmandu. The patients were followed up for three months.<h4>Results</h4>The post-COVID status of 300 patients admitted to the COVID emergency of TUTH was studied. The mean age of the patients was 46.6±15.7 years, and the proportion of male (56%) was slightly higher than female (44%). Most of the patients (81.7%) had fever on their presentation to the emergency which was followed by fatigue (81.3%) and cough (78.3%). During the post-COVID phase, fatigue was the most common persistent symptom, with 34% experiencing fatigue after 60 days and 28.3% even after 90 days from the onset of symptoms. Univariate logistic regression showed sore throat (OR 4.6; 95% CI (2.8-7.6)), rhinitis (OR 3.6; 95% CI (2.1-5.9)), fatigue (OR 3.7; 95% CI (1.8-7.6)), diarrhea (OR 4.1; 95% CI (2.4-6.9)), anosmia (OR 6.7; 95% CI (3.9-11.3)), ageusia (OR 7.8; 95% CI (4.5-13.4)) and shortness of breath (OR 14.9; 95% CI (1.8-119.6)) at admission were all predictors of post-COVID syndrome after three months.<h4>Conclusion</h4>Even after recovering from COVID-19, people with COVID-19 may develop symptoms. As a result, COVID-19's long-term consequences should not be neglected, as they may lead to increased morbidity among patients, consumption of financial resources, and added burden on the health system. |
| first_indexed | 2024-04-13T07:30:03Z |
| format | Article |
| id | doaj.art-34ffca933de644159b3830e10c0540a9 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-13T07:30:03Z |
| publishDate | 2022-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-34ffca933de644159b3830e10c0540a92022-12-22T02:56:22ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-01178e027263610.1371/journal.pone.0272636Post-COVID syndrome: A prospective study in a tertiary hospital of Nepal.Sangam ShahShreeyash Raj BhattaraiKriti BasnetYagya Raj AdhikariTara Ballav AdhikariNikita BhattaRajan ChamlagainSusan AryalSanjit Kumar SahGovinda BhandariBibek BhandariSujan PoudelPankaj PantSanta Kumar Das<h4>Introduction</h4>The post-coronavirus disease 2019 (COVID-19) syndrome is defined as the persistence of symptoms after viral clearance and the emergence of new symptoms after a few months following recovery from COVID-19. This study aimed to assess the prevalence of post-COVID-19 syndrome and the risk factors that contribute to its development.<h4>Methods</h4>This study was conducted prospectively in Tribhuvan University Teaching Hospital (TUTH), located in Maharajgunj, Kathmandu. The patients were followed up for three months.<h4>Results</h4>The post-COVID status of 300 patients admitted to the COVID emergency of TUTH was studied. The mean age of the patients was 46.6±15.7 years, and the proportion of male (56%) was slightly higher than female (44%). Most of the patients (81.7%) had fever on their presentation to the emergency which was followed by fatigue (81.3%) and cough (78.3%). During the post-COVID phase, fatigue was the most common persistent symptom, with 34% experiencing fatigue after 60 days and 28.3% even after 90 days from the onset of symptoms. Univariate logistic regression showed sore throat (OR 4.6; 95% CI (2.8-7.6)), rhinitis (OR 3.6; 95% CI (2.1-5.9)), fatigue (OR 3.7; 95% CI (1.8-7.6)), diarrhea (OR 4.1; 95% CI (2.4-6.9)), anosmia (OR 6.7; 95% CI (3.9-11.3)), ageusia (OR 7.8; 95% CI (4.5-13.4)) and shortness of breath (OR 14.9; 95% CI (1.8-119.6)) at admission were all predictors of post-COVID syndrome after three months.<h4>Conclusion</h4>Even after recovering from COVID-19, people with COVID-19 may develop symptoms. As a result, COVID-19's long-term consequences should not be neglected, as they may lead to increased morbidity among patients, consumption of financial resources, and added burden on the health system.https://doi.org/10.1371/journal.pone.0272636 |
| spellingShingle | Sangam Shah Shreeyash Raj Bhattarai Kriti Basnet Yagya Raj Adhikari Tara Ballav Adhikari Nikita Bhatta Rajan Chamlagain Susan Aryal Sanjit Kumar Sah Govinda Bhandari Bibek Bhandari Sujan Poudel Pankaj Pant Santa Kumar Das Post-COVID syndrome: A prospective study in a tertiary hospital of Nepal. PLoS ONE |
| title | Post-COVID syndrome: A prospective study in a tertiary hospital of Nepal. |
| title_full | Post-COVID syndrome: A prospective study in a tertiary hospital of Nepal. |
| title_fullStr | Post-COVID syndrome: A prospective study in a tertiary hospital of Nepal. |
| title_full_unstemmed | Post-COVID syndrome: A prospective study in a tertiary hospital of Nepal. |
| title_short | Post-COVID syndrome: A prospective study in a tertiary hospital of Nepal. |
| title_sort | post covid syndrome a prospective study in a tertiary hospital of nepal |
| url | https://doi.org/10.1371/journal.pone.0272636 |
| work_keys_str_mv | AT sangamshah postcovidsyndromeaprospectivestudyinatertiaryhospitalofnepal AT shreeyashrajbhattarai postcovidsyndromeaprospectivestudyinatertiaryhospitalofnepal AT kritibasnet postcovidsyndromeaprospectivestudyinatertiaryhospitalofnepal AT yagyarajadhikari postcovidsyndromeaprospectivestudyinatertiaryhospitalofnepal AT taraballavadhikari postcovidsyndromeaprospectivestudyinatertiaryhospitalofnepal AT nikitabhatta postcovidsyndromeaprospectivestudyinatertiaryhospitalofnepal AT rajanchamlagain postcovidsyndromeaprospectivestudyinatertiaryhospitalofnepal AT susanaryal postcovidsyndromeaprospectivestudyinatertiaryhospitalofnepal AT sanjitkumarsah postcovidsyndromeaprospectivestudyinatertiaryhospitalofnepal AT govindabhandari postcovidsyndromeaprospectivestudyinatertiaryhospitalofnepal AT bibekbhandari postcovidsyndromeaprospectivestudyinatertiaryhospitalofnepal AT sujanpoudel postcovidsyndromeaprospectivestudyinatertiaryhospitalofnepal AT pankajpant postcovidsyndromeaprospectivestudyinatertiaryhospitalofnepal AT santakumardas postcovidsyndromeaprospectivestudyinatertiaryhospitalofnepal |