Analysis of Geometric and Hemodynamic Profiles in Rat Arteriovenous Fistula Following PDE5A Inhibition

Analysis of Geometric and Hemodynamic Profiles in Rat Arteriovenous Fistula Following PDE5A Inhibition

Arteriovenous fistula (AVF) is essential for chronic kidney disease (CKD) patients on hemodialysis, but treatment for AVF maturation failure remains an unmet clinical need. Successful AVF remodeling occurs through sufficient lumen expansion to increase AVF blood flow and lumen area. Aberrant blood f...

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Bibliographic Details
Main Authors:	Hannah Northrup, Maheshika Somarathna, Savanna Corless, Isabelle Falzon, John Totenhagen, Timmy Lee, Yan-Ting Shiu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-12-01
Series:	Frontiers in Bioengineering and Biotechnology
Subjects:	arteriovenous fistula computational fluid dynamics shear stress outward remodeling vessel dilation
Online Access:	https://www.frontiersin.org/articles/10.3389/fbioe.2021.779043/full

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