MIS-C and Visceral Leishmaniasis Co-occurence: Has the Clinic of Other Diseases Masked in the Pandemia?

At the end of 2019, the newly detected severe acute respiratory syndrome-coronavirus (COVID)-2 in China spread rapidly and caused a global epidemic. It has been observed that the virus, which is the cause of COVID-2019 and can cause severe acute respiratory failure, later causes a hyperinflammatory...

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Main Authors: Merve Kılıç Çil, Metin Çil, Songül Uzgelir, Orkun Tolunay, Ümit Çelik
Format: Article
Language:English
Published: Galenos Yayinevi 2022-09-01
Series:Türkiye Parazitoloji Dergisi
Subjects:
Online Access: http://www.turkiyeparazitolderg.org/archives/archive-detail/article-preview/ms-c-and-visceral-leishmaniasis-co-occurence-has-t/52900
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author Merve Kılıç Çil
Metin Çil
Songül Uzgelir
Orkun Tolunay
Ümit Çelik
author_facet Merve Kılıç Çil
Metin Çil
Songül Uzgelir
Orkun Tolunay
Ümit Çelik
author_sort Merve Kılıç Çil
collection DOAJ
description At the end of 2019, the newly detected severe acute respiratory syndrome-coronavirus (COVID)-2 in China spread rapidly and caused a global epidemic. It has been observed that the virus, which is the cause of COVID-2019 and can cause severe acute respiratory failure, later causes a hyperinflammatory picture and causes a clinical picture similar to Kawasaki disease. Fever, cardiac involvement and rash are the most common findings in this picture, which is called multisystem inflammatory syndrome (MIS-C). Although its pathophysiology is not fully known yet, the most common cause is thought to be post-infection immune dysregulation. Visceral leishmaniasis (VL) is a zoonosis in which Leishmania infantum and rarely Leishmania donovani are the agents and can cause a similar clinical picture. In this text; we discussed a patient who was followed up with a diagnosis of COVID-associated MIS-C, but without an adequate response in his clinic with MIS-C treatment, and was diagnosed with VL with further examinations. To our knowledge, this is the first MIS-C and VL co-occurence in the literature.
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spelling doaj.art-3502aad871b64a71bdd131779e1d07192023-02-15T16:11:12ZengGalenos YayineviTürkiye Parazitoloji Dergisi1300-63202146-30772022-09-0146324224510.4274/tpd.galenos.2022.2829013049054MIS-C and Visceral Leishmaniasis Co-occurence: Has the Clinic of Other Diseases Masked in the Pandemia?Merve Kılıç Çil0Metin Çil1Songül Uzgelir2Orkun Tolunay3Ümit Çelik4 Sağlık Bilimleri Üniversitesi, Adana Şehir ve Eğitim Araştırma Hastanesi, Çocuk Enfeksiyon Kliniği, Adana, Türkiye Sağlık Bilimleri Üniversitesi, Adana Şehir ve Eğitim Araştırma Hastanesi, Çocuk Hematoloji ve Onkoloji Kliniği, Adana, Türkiye Sağlık Bilimleri Üniversitesi, Adana Şehir ve Eğitim Araştırma Hastanesi, Çocuk Sağlığı ve Hastalıkları Kliniği, Adana, Türkiye Sağlık Bilimleri Üniversitesi, Adana Şehir ve Eğitim Araştırma Hastanesi, Çocuk Sağlığı ve Hastalıkları Kliniği, Adana, Türkiye Sağlık Bilimleri Üniversitesi, Adana Şehir ve Eğitim Araştırma Hastanesi, Çocuk Enfeksiyon Kliniği, Adana, Türkiye At the end of 2019, the newly detected severe acute respiratory syndrome-coronavirus (COVID)-2 in China spread rapidly and caused a global epidemic. It has been observed that the virus, which is the cause of COVID-2019 and can cause severe acute respiratory failure, later causes a hyperinflammatory picture and causes a clinical picture similar to Kawasaki disease. Fever, cardiac involvement and rash are the most common findings in this picture, which is called multisystem inflammatory syndrome (MIS-C). Although its pathophysiology is not fully known yet, the most common cause is thought to be post-infection immune dysregulation. Visceral leishmaniasis (VL) is a zoonosis in which Leishmania infantum and rarely Leishmania donovani are the agents and can cause a similar clinical picture. In this text; we discussed a patient who was followed up with a diagnosis of COVID-associated MIS-C, but without an adequate response in his clinic with MIS-C treatment, and was diagnosed with VL with further examinations. To our knowledge, this is the first MIS-C and VL co-occurence in the literature. http://www.turkiyeparazitolderg.org/archives/archive-detail/article-preview/ms-c-and-visceral-leishmaniasis-co-occurence-has-t/52900 childmultisystem inflammatory syndromevisceral leishmaniasissars-cov-2
spellingShingle Merve Kılıç Çil
Metin Çil
Songül Uzgelir
Orkun Tolunay
Ümit Çelik
MIS-C and Visceral Leishmaniasis Co-occurence: Has the Clinic of Other Diseases Masked in the Pandemia?
Türkiye Parazitoloji Dergisi
child
multisystem inflammatory syndrome
visceral leishmaniasis
sars-cov-2
title MIS-C and Visceral Leishmaniasis Co-occurence: Has the Clinic of Other Diseases Masked in the Pandemia?
title_full MIS-C and Visceral Leishmaniasis Co-occurence: Has the Clinic of Other Diseases Masked in the Pandemia?
title_fullStr MIS-C and Visceral Leishmaniasis Co-occurence: Has the Clinic of Other Diseases Masked in the Pandemia?
title_full_unstemmed MIS-C and Visceral Leishmaniasis Co-occurence: Has the Clinic of Other Diseases Masked in the Pandemia?
title_short MIS-C and Visceral Leishmaniasis Co-occurence: Has the Clinic of Other Diseases Masked in the Pandemia?
title_sort mis c and visceral leishmaniasis co occurence has the clinic of other diseases masked in the pandemia
topic child
multisystem inflammatory syndrome
visceral leishmaniasis
sars-cov-2
url http://www.turkiyeparazitolderg.org/archives/archive-detail/article-preview/ms-c-and-visceral-leishmaniasis-co-occurence-has-t/52900
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AT metincil miscandvisceralleishmaniasiscooccurencehastheclinicofotherdiseasesmaskedinthepandemia
AT songuluzgelir miscandvisceralleishmaniasiscooccurencehastheclinicofotherdiseasesmaskedinthepandemia
AT orkuntolunay miscandvisceralleishmaniasiscooccurencehastheclinicofotherdiseasesmaskedinthepandemia
AT umitcelik miscandvisceralleishmaniasiscooccurencehastheclinicofotherdiseasesmaskedinthepandemia