Drug-coated Balloons in the Neurovascular Setting: A Comprehensive, Systematic Review of Current Use and Indications

Background: Drug-coated balloons (DCB) are an established tool in the prevention and treatment of coronary and peripheral artery restenosis. The underlying effects of restenosis resemble those in the neurovascular field, yet data on the use of DCB in cervical and intracranial arteries is rare. Metho...

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Main Authors: Philipp von Gottberg, Alexandru Cimpoca, Christina Wendl, José E. Cohen, Ulrich Speck, Hans Henkes
Format: Article
Language:English
Published: IMR Press 2022-04-01
Series:Reviews in Cardiovascular Medicine
Subjects:
Online Access:https://www.imrpress.com/journal/RCM/23/4/10.31083/j.rcm2304128
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author Philipp von Gottberg
Alexandru Cimpoca
Christina Wendl
José E. Cohen
Ulrich Speck
Hans Henkes
author_facet Philipp von Gottberg
Alexandru Cimpoca
Christina Wendl
José E. Cohen
Ulrich Speck
Hans Henkes
author_sort Philipp von Gottberg
collection DOAJ
description Background: Drug-coated balloons (DCB) are an established tool in the prevention and treatment of coronary and peripheral artery restenosis. The underlying effects of restenosis resemble those in the neurovascular field, yet data on the use of DCB in cervical and intracranial arteries is rare. Methods: Medline, and international and major national guidelines and recommendations were systematically searched for data addressing the use of DCB in the neurovascular setting. Results: Of the 1448 relevant records found in Medline, 166 publications were considered for this review. Conclusions: Data on the use of DCB in the neurovascular setting show a possible benefit over preceding alternatives, such as self-expanding stents, and balloon-mounted or drug-eluting stents. Nonetheless, the role of DCB remains under-researched, and publications remain lacking.
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spelling doaj.art-350b426752ce40fe94092f340f44855b2022-12-22T01:52:50ZengIMR PressReviews in Cardiovascular Medicine1530-65502022-04-0123412810.31083/j.rcm2304128S1530-6550(22)00452-5Drug-coated Balloons in the Neurovascular Setting: A Comprehensive, Systematic Review of Current Use and IndicationsPhilipp von Gottberg0Alexandru Cimpoca1Christina Wendl2José E. Cohen3Ulrich Speck4Hans Henkes5Neuroradiologische Klinik, Klinikum Stuttgart, 70174 Stuttgart, GermanyNeuroradiologische Klinik, Klinikum Stuttgart, 70174 Stuttgart, GermanyNeuroradiologisches Zentrum, Institut für Röntgendiagnostik, Universitätsklinikum Regensburg, 93053 Regensburg, GermanyDepartment of Neurosurgery, Neuroendovascular Center, Hadassah University Hospital, 91120 Jerusalem, IsraelKlinik für Radiologie, Charité Universitätsmedizin Berlin, 10117 Berlin, GermanyNeuroradiologische Klinik, Klinikum Stuttgart, 70174 Stuttgart, GermanyBackground: Drug-coated balloons (DCB) are an established tool in the prevention and treatment of coronary and peripheral artery restenosis. The underlying effects of restenosis resemble those in the neurovascular field, yet data on the use of DCB in cervical and intracranial arteries is rare. Methods: Medline, and international and major national guidelines and recommendations were systematically searched for data addressing the use of DCB in the neurovascular setting. Results: Of the 1448 relevant records found in Medline, 166 publications were considered for this review. Conclusions: Data on the use of DCB in the neurovascular setting show a possible benefit over preceding alternatives, such as self-expanding stents, and balloon-mounted or drug-eluting stents. Nonetheless, the role of DCB remains under-researched, and publications remain lacking.https://www.imrpress.com/journal/RCM/23/4/10.31083/j.rcm2304128drug-coated balloonspercutaneous transluminal angioplastyneurovascularneurointerventionalarterial stenosiscarotid artery stenosisintracranial atherosclerotic stenosisstrokepaclitaxel
spellingShingle Philipp von Gottberg
Alexandru Cimpoca
Christina Wendl
José E. Cohen
Ulrich Speck
Hans Henkes
Drug-coated Balloons in the Neurovascular Setting: A Comprehensive, Systematic Review of Current Use and Indications
Reviews in Cardiovascular Medicine
drug-coated balloons
percutaneous transluminal angioplasty
neurovascular
neurointerventional
arterial stenosis
carotid artery stenosis
intracranial atherosclerotic stenosis
stroke
paclitaxel
title Drug-coated Balloons in the Neurovascular Setting: A Comprehensive, Systematic Review of Current Use and Indications
title_full Drug-coated Balloons in the Neurovascular Setting: A Comprehensive, Systematic Review of Current Use and Indications
title_fullStr Drug-coated Balloons in the Neurovascular Setting: A Comprehensive, Systematic Review of Current Use and Indications
title_full_unstemmed Drug-coated Balloons in the Neurovascular Setting: A Comprehensive, Systematic Review of Current Use and Indications
title_short Drug-coated Balloons in the Neurovascular Setting: A Comprehensive, Systematic Review of Current Use and Indications
title_sort drug coated balloons in the neurovascular setting a comprehensive systematic review of current use and indications
topic drug-coated balloons
percutaneous transluminal angioplasty
neurovascular
neurointerventional
arterial stenosis
carotid artery stenosis
intracranial atherosclerotic stenosis
stroke
paclitaxel
url https://www.imrpress.com/journal/RCM/23/4/10.31083/j.rcm2304128
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