Analysis of F2-isoprostanes in plasma of pregnant women by HPLC-MS/MS using a column packed with core-shell particles

Analysis of F2-isoprostanes in plasma of pregnant women by HPLC-MS/MS using a column packed with core-shell particles

Plasma F2-isoprostanes (F2-isoPs) are reliable biomarkers of oxidative stress. Several possible F2-isoPs are generated by the oxidation of arachidonic acid esterified in phospholipids. The separation of these isomers represents a technical challenge for rapid and selective determination. We have dev...

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Bibliographic Details
Main Authors:	Jessica Larose, Pierre Julien, Jean-François Bilodeau
Format:	Article
Language:	English
Published:	Elsevier 2013-05-01
Series:	Journal of Lipid Research
Subjects:	oxidative stress pregnancy mass spectrometry 8-iso-PGF2α F2-isoprostane high-performance liquid chromatography
Online Access:	http://www.sciencedirect.com/science/article/pii/S002222752042187X

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