An EGF- and Curcumin-Co-Encapsulated Nanostructured Lipid Carrier Accelerates Chronic-Wound Healing in Diabetic Rats

An EGF- and Curcumin-Co-Encapsulated Nanostructured Lipid Carrier Accelerates Chronic-Wound Healing in Diabetic Rats

Nanostructured lipid carriers (NLC) are capable of encapsulating hydrophilic and lipophilic drugs. The present study developed an NLC containing epidermal growth factor (EGF) and curcumin (EGF–Cur-NLC). EGF–Cur-NLC was prepared by a modified water-in-oil-in-water (w/o/w) double-emulsion method. The...

Full description

Bibliographic Details
Main Authors:	Hye-Jin Lee, Moses Jeong, Young-Guk Na, Sung-Jin Kim, Hong-Ki Lee, Cheong-Weon Cho
Format:	Article
Language:	English
Published:	MDPI AG 2020-10-01
Series:	Molecules
Subjects:	EGF curcumin nanostructured lipid carrier chronic-wound healing antioxidant effect
Online Access:	https://www.mdpi.com/1420-3049/25/20/4610

Similar Items

Pharmacokinetic studies and anticancer activity of curcumin-loaded nanostructured lipid carriers
by: Wang Fengling, et al.
Published: (2017-09-01)

EGF and curcumin co-encapsulated nanoparticle/hydrogel system as potent skin regeneration agent
by: Li X, et al.
Published: (2016-08-01)

Toward a Platform for the Treatment of Burns: An Assessment of Nanoemulsions vs. Nanostructured Lipid Carriers Loaded with Curcumin
by: Gabriela de Moraes Soares Araújo, et al.
Published: (2023-12-01)

Preparation and In Vitro Evaluation of Glycyrrhetinic Acid-Modified Curcumin-Loaded Nanostructured Lipid Carriers
by: Yang Chu, et al.
Published: (2014-02-01)

Natural Stabilizers and Nanostructured Lipid Carrier Entrapment for Photosensitive Compounds, Curcumin and Capsaicin
by: Wipanan Jandang, et al.
Published: (2024-03-01)

Dual Nanostructured Lipid Carriers/Hydrogel System for Delivery of Curcumin for Topical Skin Applications
by: Rosa Calderon-Jacinto, et al.
Published: (2022-06-01)

Optimization and evaluation of microwave-assisted curcumin-loaded nanostructured lipid carriers: a green approach
by: Sunidhi Lohan, et al.
Published: (2023-12-01)

Effects of Preparation Temperature and Liquid-Solid Lipid Composition to Curcumin-Nanostructured Lipid Carrier Characteristics Fabricated by Microfluidic Technique
by: Ridho Arief Al Rasyid, et al.
Published: (2023-08-01)

The Delivery Strategy of Paclitaxel Nanostructured Lipid Carrier Coated with Platelet Membrane
by: Ki-Hyun Bang, et al.
Published: (2019-06-01)

Antineoplastics Encapsulated in Nanostructured Lipid Carriers
by: Gustavo Henrique Rodrigues da Silva, et al.
Published: (2021-11-01)

Effects of Curcumin on Epidermal Growth Factor in Proliferative Vitreoretinopathy
by: Yan-xin Ren, et al.
Published: (2018-07-01)

Nanostructure Lipid Carrier of Curcumin Co-Delivered with Linalool and Geraniol Monoterpenes as Acetylcholinesterase Inhibitor of <i>Culex pipiens</i>
by: Ibrahim Taha Radwan, et al.
Published: (2024-01-01)

Curcumin-loaded nanostructured lipid carriers prepared using Peceol™ and olive oil in photodynamic therapy: development and application in breast cancer cell line
by: Kamel AE, et al.
Published: (2019-07-01)

Nanostructured lipid carriers: Promising delivery systems for encapsulation of food ingredients
by: Farnaz Ahmadzadeh Nobari Azar, et al.
Published: (2020-12-01)

Improved Diabetic Wound Healing by EGF Encapsulation in Gelatin-Alginate Coacervates
by: Seonghee Jeong, et al.
Published: (2020-04-01)

Accelerated infected wound healing by topical application of encapsulated Rosemary essential oil into nanostructured lipid carriers
by: Keyvan Khezri, et al.
Published: (2019-12-01)

Exploitation of traditional healing properties, using the nanotechnology’s advantages: The case of curcumin
by: Angeliki Liakopoulou, et al.
Published: (2021-01-01)

Sequential delivery of dual drugs with nanostructured lipid carriers for improving synergistic tumor treatment effect
by: Man Xu, et al.
Published: (2020-01-01)

Systemic Design and Evaluation of Ticagrelor-Loaded Nanostructured Lipid Carriers for Enhancing Bioavailability and Antiplatelet Activity
by: Gi-Ho Son, et al.
Published: (2019-05-01)

Enhanced efficacy of curcumin with phosphatidylserine-decorated nanoparticles in the treatment of hepatic fibrosis
by: Ji Wang, et al.
Published: (2018-01-01)

The Improvement of Skin Whitening of Phenylethyl Resorcinol by Nanostructured Lipid Carriers
by: Bo-Sik Kim, et al.
Published: (2017-08-01)

Nanostructured lipid carrier-based smart gel: a delivery platform for intra-articular therapeutics
by: Chetan Shinde, et al.
Published: (2021-01-01)

Small GTP‐binding protein Rap1 mediates EGF and HB‐EGF signaling and modulates EGF receptor expression in HTR‐8/SVneo extravillous trophoblast cells
by: Mikihiro Yoshie, et al.
Published: (2023-01-01)

Curcumin-loaded nanostructured lipid carrier induced apoptosis in human HepG2 cells through activation of the DR5/caspase-mediated extrinsic apoptosis pathway
by: Wang Fengling, et al.
Published: (2020-06-01)

Fabrication, Evaluation, and Antioxidant Properties of Carrier-Free Curcumin Nanoparticles
by: Jinwei Wu, et al.
Published: (2023-01-01)

Treatment of colitis by oral negatively charged nanostructured curcumin in rats
by: Lívia Medeiros Soares Celani, et al.
Published: (2022-08-01)

N-acetyl-L-cysteine functionalized nanostructured lipid carrier for improving oral bioavailability of curcumin: preparation, in vitro and in vivo evaluations
by: Cihui Tian, et al.
Published: (2017-01-01)

Carrier-free curcumin nanoassemblies for enhancing therapy effects in inflammation related disease
by: Liangjun Zhang, et al.
Published: (2022-10-01)

Topical Allopurinol-Loaded Nanostructured Lipid Carriers: A Novel Approach for Wound Healing Management
by: Carla Varrica, et al.
Published: (2021-11-01)

Improvement of Cell Culture Methods for the Successful Generation of Human Keratinocyte Primary Cell Cultures Using EGF-Loaded Nanostructured Lipid Carriers
by: Jesús Chato-Astrain, et al.
Published: (2021-11-01)

Characterization and toxicity of citral incorporated with nanostructured lipid carrier
by: Noraini Nordin, et al.
Published: (2018-01-01)

Development of Computational In Silico Model for Nano Lipid Carrier Formulation of Curcumin
by: Omar Waleed Abduljaleel Albasri, et al.
Published: (2023-02-01)

Comparison of Fabrication Technique and Carrier Oil to Curcumin Nanoemulsion Properties
by: Zubaidah Ningsih, et al.
Published: (2023-04-01)

Nanostructured Lipid Carrier Co-Loaded with Docetaxel and Magnetic Nanoparticles: Physicochemical Characterization and In Vitro Evaluation
by: Auni Hamimi Idris, et al.
Published: (2023-04-01)

Enhancement of Skin Wound Healing by rhEGF-Loaded Carboxymethyl Chitosan Nanoparticles
by: Pei Zhang, et al.
Published: (2020-07-01)

Acute and subacute toxicity profiles of thymoquinone-loaded nanostructured lipid carrier in BALB/c mice
by: Ong YS, et al.
Published: (2016-11-01)

EGF receptor signaling, phosphorylation, ubiquitylation and endocytosis in tumors in vivo
by: Itziar Pinilla-Macua, et al.
Published: (2017-12-01)

Sarcosine May Induce EGF Production or Inhibit the Decline in EGF Concentrations in Patients with Chronic Schizophrenia (Results of the PULSAR Study)
by: Agnieszka Pawlak, et al.
Published: (2023-11-01)

Sustained-release genistein from nanostructured lipid carrier suppresses human lens epithelial cell growth
by: Jin-Lu Liu, et al.
Published: (2016-05-01)

Relevance of LIF and EGF on Mouse Preimplantation Embryo Development
by: Iraj Amiri, et al.
Published: (2008-01-01)