Protective Effect of Phenolic Compounds Isolated from Mugwort (Artemisia argyi) against Contrast-Induced Apoptosis in Kidney Epithelium Cell Line LLC-PK1

Protective Effect of Phenolic Compounds Isolated from Mugwort (Artemisia argyi) against Contrast-Induced Apoptosis in Kidney Epithelium Cell Line LLC-PK1

We investigated whether 14 phenolic compounds isolated from Artemisia argyi could prevent the apoptotic damage caused by iodixanol, an iodinated contrast agent, on LLC-PK1 cells. Iodixanol was used to induce cytotoxicity in LLC-PK1 cells. Apoptotic cell death was observed as the fluorescence intensi...

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Bibliographic Details
Main Authors: Kem Ok Kim, Dahae Lee, Nguyen Tuan Hiep, Ji Hoon Song, Hae-Jeung Lee, Dongho Lee, Ki Sung Kang
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Molecules
Subjects:
contrast agent
iodixanol
cytotoxicity
MAPKs
caspase-3
kidney injury molecule-1
Online Access:http://www.mdpi.com/1420-3049/24/1/195

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