Multi-Step Extracellular Matrix Remodelling and Stiffening in the Development of Idiopathic Pulmonary Fibrosis

The extracellular matrix (ECM) of the lung is a filamentous network composed mainly of collagens, elastin, and proteoglycans that provides structural and physical support to its populating cells. Proliferation, migration and overall behaviour of those cells is greatly determined by micromechanical q...

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Bibliographic Details
Main Authors: Constança Júnior, Anna Ulldemolins, Maria Narciso, Isaac Almendros, Ramon Farré, Daniel Navajas, Javier López, Mar Eroles, Felix Rico, Núria Gavara
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/2/1708