ASYMPTOMATIC COURSE OF LUNG DAMAGE IN GRANULOMATOSIS WITH POLYANGIITIS (WEGENER’S)

Lung damage, along with the pathology of the upper respiratory tract and kidneys, constitute the classic triad of Wegener's granulomatosis with polyangiitis (GPA). The special features of pulmonary pathology in this disease include the possibility of asymptomatic course. A case of asymptomatic...

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Main Author: Tat’yana V Beketova
Format: Article
Language:Russian
Published: IMA PRESS LLC 2014-03-01
Series:Научно-практическая ревматология
Subjects:
Online Access:https://rsp.mediar-press.net/rsp/article/view/1689
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author Tat’yana V Beketova
author_facet Tat’yana V Beketova
author_sort Tat’yana V Beketova
collection DOAJ
description Lung damage, along with the pathology of the upper respiratory tract and kidneys, constitute the classic triad of Wegener's granulomatosis with polyangiitis (GPA). The special features of pulmonary pathology in this disease include the possibility of asymptomatic course. A case of asymptomatic lung damage in a patient with GPA has been reported. Despite clear signs of drug-induced clinical and laboratory remission, routine computed tomography (CT) revealed progressive changes in lung parenchyma as multiple foci with destruction, which regressed after treatment with cyclophosphamide. The importance of instrumental examination, including CT of the chest at the onset of GPA and during the subsequent follow-up, was emphasized.
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spelling doaj.art-3517a2d8c70b4c098815fe3193ab2fe72025-03-02T13:23:39ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922014-03-0152110210410.14412/1995-4484-2014-102-1041626ASYMPTOMATIC COURSE OF LUNG DAMAGE IN GRANULOMATOSIS WITH POLYANGIITIS (WEGENER’S)Tat’yana V Beketova0V.A. Nasonova Research Institute of Rheumatology, Russian Academy of Medical Sciences, Moscow, RussiaLung damage, along with the pathology of the upper respiratory tract and kidneys, constitute the classic triad of Wegener's granulomatosis with polyangiitis (GPA). The special features of pulmonary pathology in this disease include the possibility of asymptomatic course. A case of asymptomatic lung damage in a patient with GPA has been reported. Despite clear signs of drug-induced clinical and laboratory remission, routine computed tomography (CT) revealed progressive changes in lung parenchyma as multiple foci with destruction, which regressed after treatment with cyclophosphamide. The importance of instrumental examination, including CT of the chest at the onset of GPA and during the subsequent follow-up, was emphasized.https://rsp.mediar-press.net/rsp/article/view/1689anca-associated vasculitissystemic vasculitisgranulomatosis with polyangiitis (wegener’s)lung damage
spellingShingle Tat’yana V Beketova
ASYMPTOMATIC COURSE OF LUNG DAMAGE IN GRANULOMATOSIS WITH POLYANGIITIS (WEGENER’S)
Научно-практическая ревматология
anca-associated vasculitis
systemic vasculitis
granulomatosis with polyangiitis (wegener’s)
lung damage
title ASYMPTOMATIC COURSE OF LUNG DAMAGE IN GRANULOMATOSIS WITH POLYANGIITIS (WEGENER’S)
title_full ASYMPTOMATIC COURSE OF LUNG DAMAGE IN GRANULOMATOSIS WITH POLYANGIITIS (WEGENER’S)
title_fullStr ASYMPTOMATIC COURSE OF LUNG DAMAGE IN GRANULOMATOSIS WITH POLYANGIITIS (WEGENER’S)
title_full_unstemmed ASYMPTOMATIC COURSE OF LUNG DAMAGE IN GRANULOMATOSIS WITH POLYANGIITIS (WEGENER’S)
title_short ASYMPTOMATIC COURSE OF LUNG DAMAGE IN GRANULOMATOSIS WITH POLYANGIITIS (WEGENER’S)
title_sort asymptomatic course of lung damage in granulomatosis with polyangiitis wegener s
topic anca-associated vasculitis
systemic vasculitis
granulomatosis with polyangiitis (wegener’s)
lung damage
url https://rsp.mediar-press.net/rsp/article/view/1689
work_keys_str_mv AT tatyanavbeketova asymptomaticcourseoflungdamageingranulomatosiswithpolyangiitiswegeners