Mechanism of Smilax china L. in the treatment of intrauterine adhesions based on network pharmacology, molecular docking and experimental validation

Mechanism of Smilax china L. in the treatment of intrauterine adhesions based on network pharmacology, molecular docking and experimental validation

Abstract Background Smilax china L. (SCL) is a traditional herbal medicine for the potential treatment of intrauterine adhesion (IUA). However, the mechanisms of action have not yet been determined. In this study, we explored the effects and mechanisms of SCL in IUA by network pharmacology, molecula...

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Bibliographic Details
Main Authors: Tingting Shi, Chuqi Hou, Yongzhen Duan, Yuliang Li, Wenqin Liu, Peixian Huang, Yuhua Zhou, Shanshan Yu, Luyao Song
Format: Article
Language:English
Published: BMC 2024-04-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Intrauterine adhesion
Smilax china L.
Astilbin
Molecular docking
Network pharmacology
PI3K/AKT
Online Access:https://doi.org/10.1186/s12906-024-04414-4

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