Research progress on the mechanism of traditional Chinese medicine regulating intestinal microbiota to combat influenza a virus infection
Abstract Influenza A viruses (IAV) are a prevalent respiratory pathogen that can cause seasonal flu and global pandemics, posing a significant global public health threat. Emerging research suggests that IAV infections may disrupt the balance of gut microbiota, while gut dysbiosis can affect disease...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-11-01
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| Series: | Virology Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12985-023-02228-3 |
| _version_ | 1797578152550072320 |
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| author | LanYing Ma Lingyun Ji Tong Wang Zhe Zhai PeiWei Su YaNan Zhang Yuan Wang WenXiao Zhao ZhiChun Wu HuaYun Yu HaiJun Zhao |
| author_facet | LanYing Ma Lingyun Ji Tong Wang Zhe Zhai PeiWei Su YaNan Zhang Yuan Wang WenXiao Zhao ZhiChun Wu HuaYun Yu HaiJun Zhao |
| author_sort | LanYing Ma |
| collection | DOAJ |
| description | Abstract Influenza A viruses (IAV) are a prevalent respiratory pathogen that can cause seasonal flu and global pandemics, posing a significant global public health threat. Emerging research suggests that IAV infections may disrupt the balance of gut microbiota, while gut dysbiosis can affect disease progression in IAV patients. Therefore, restoring gut microbiota balance may represent a promising therapeutic target for IAV infections. Traditional Chinese medicine, with its ability to regulate gut microbiota, offers significant potential in preventing and treating IAV. This article provides a comprehensive review of the relationship between IAV and gut microbiota, highlighting the impact of gut microbiota on IAV infections. It also explores the mechanisms and role of traditional Chinese medicine in regulating gut microbiota for the prevention and treatment of IAV, presenting novel research avenues for traditional Chinese medicine-based IAV treatments. |
| first_indexed | 2024-03-10T22:18:11Z |
| format | Article |
| id | doaj.art-351f898db5f74927895e6aa9dc4e1581 |
| institution | Directory Open Access Journal |
| issn | 1743-422X |
| language | English |
| last_indexed | 2024-03-10T22:18:11Z |
| publishDate | 2023-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Virology Journal |
| spelling | doaj.art-351f898db5f74927895e6aa9dc4e15812023-11-19T12:21:51ZengBMCVirology Journal1743-422X2023-11-012011910.1186/s12985-023-02228-3Research progress on the mechanism of traditional Chinese medicine regulating intestinal microbiota to combat influenza a virus infectionLanYing Ma0Lingyun Ji1Tong Wang2Zhe Zhai3PeiWei Su4YaNan Zhang5Yuan Wang6WenXiao Zhao7ZhiChun Wu8HuaYun Yu9HaiJun Zhao10College of Traditional Chinese Medicine, Shandong University of Traditional Chinese MedicineFirst Clinical Medical College, Shandong University of Traditional Chinese MedicineSchool of Nursing, Shandong University of Traditional Chinese MedicineCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese MedicineCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese MedicineCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese MedicineCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese MedicineCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese MedicineCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese MedicineCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese MedicineCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese MedicineAbstract Influenza A viruses (IAV) are a prevalent respiratory pathogen that can cause seasonal flu and global pandemics, posing a significant global public health threat. Emerging research suggests that IAV infections may disrupt the balance of gut microbiota, while gut dysbiosis can affect disease progression in IAV patients. Therefore, restoring gut microbiota balance may represent a promising therapeutic target for IAV infections. Traditional Chinese medicine, with its ability to regulate gut microbiota, offers significant potential in preventing and treating IAV. This article provides a comprehensive review of the relationship between IAV and gut microbiota, highlighting the impact of gut microbiota on IAV infections. It also explores the mechanisms and role of traditional Chinese medicine in regulating gut microbiota for the prevention and treatment of IAV, presenting novel research avenues for traditional Chinese medicine-based IAV treatments.https://doi.org/10.1186/s12985-023-02228-3Influenza a virusGut microbiotaTraditional Chinese medicineAnd respiratory virus Infections |
| spellingShingle | LanYing Ma Lingyun Ji Tong Wang Zhe Zhai PeiWei Su YaNan Zhang Yuan Wang WenXiao Zhao ZhiChun Wu HuaYun Yu HaiJun Zhao Research progress on the mechanism of traditional Chinese medicine regulating intestinal microbiota to combat influenza a virus infection Virology Journal Influenza a virus Gut microbiota Traditional Chinese medicine And respiratory virus Infections |
| title | Research progress on the mechanism of traditional Chinese medicine regulating intestinal microbiota to combat influenza a virus infection |
| title_full | Research progress on the mechanism of traditional Chinese medicine regulating intestinal microbiota to combat influenza a virus infection |
| title_fullStr | Research progress on the mechanism of traditional Chinese medicine regulating intestinal microbiota to combat influenza a virus infection |
| title_full_unstemmed | Research progress on the mechanism of traditional Chinese medicine regulating intestinal microbiota to combat influenza a virus infection |
| title_short | Research progress on the mechanism of traditional Chinese medicine regulating intestinal microbiota to combat influenza a virus infection |
| title_sort | research progress on the mechanism of traditional chinese medicine regulating intestinal microbiota to combat influenza a virus infection |
| topic | Influenza a virus Gut microbiota Traditional Chinese medicine And respiratory virus Infections |
| url | https://doi.org/10.1186/s12985-023-02228-3 |
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