GLUT-1 Enhances Glycolysis, Oxidative Stress, and Fibroblast Proliferation in Keloid

GLUT-1 Enhances Glycolysis, Oxidative Stress, and Fibroblast Proliferation in Keloid

A keloid is a fibroproliferative skin tumor. Proliferating keloid fibroblasts (KFs) demand active metabolic utilization. The contributing roles of glycolysis and glucose metabolism in keloid fibroproliferation remain unclear. This study aims to determine the regulation of glycolysis and glucose meta...

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Bibliographic Details
Main Authors: Ying-Yi Lu, Chieh-Hsin Wu, Chien-Hui Hong, Kee-Lung Chang, Chih-Hung Lee
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Life
Subjects:
glucose transporter 1 (GLUT-1)
glycolysis
keloids
proliferation
reactive oxygen species (ROS)
Online Access:https://www.mdpi.com/2075-1729/11/6/505

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