Single-Cell Sequencing Analysis of the db/db Mouse Hippocampus Reveals Cell-Type-Specific Insights Into the Pathobiology of Diabetes-Associated Cognitive Dysfunction

Single-Cell Sequencing Analysis of the db/db Mouse Hippocampus Reveals Cell-Type-Specific Insights Into the Pathobiology of Diabetes-Associated Cognitive Dysfunction

Diabetes-associated cognitive decline (DCD), is one of the complications of diabetes, which is characterized by a series of neurophysiological and pathological abnormalities. However, the exact pathogenesis of DCD is still unknown. Single-cell RNA sequencing (scRNA-seq) could discover unusual subpop...

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Bibliographic Details
Main Authors: Shizhan Ma, Wenkai Bi, Xueying Liu, Shangbin Li, Yaxin Qiu, Chengcheng Huang, Renjun Lv, Qingqing Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Endocrinology
Subjects:
diabetes-associated cognitive dysfunction
hippocampus
microglia
inflammation
single-cell transcriptomics
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.891039/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.891039/full

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