Effect of Xanthium Strumarium on HIV-1 5′-LTR Transcriptional Activity and Viral Reactivation in Latently Infected Cells

Effect of Xanthium Strumarium on HIV-1 5′-LTR Transcriptional Activity and Viral Reactivation in Latently Infected Cells

Chinese herbal medicines (CHMs) are widely used in Asian countries. They show multiple pharmacological activities, including antiviral activities. The 5′-long terminal repeat (LTR) region of HIV-1, required for viral transcription, is a potential drug target for HIV-1 reactivation and intrinsic cell...

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Bibliographic Details
Main Authors: Chao-Jung Chen, Mu-Lin Chiu, Chien-Hui Hung, Wen-Miin Liang, Mao-Wang Ho, Ting-Hsu Lin, Xiang Liu, Hsinyi Tsang, Chiu-Chu Liao, Shao-Mei Huang, Yi-Fang Wu, Yang-Chang Wu, Te-Mao Li, Fuu-Jen Tsai, Ying-Ju Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Pharmacology
Subjects:
human immunodeficiency virus type 1 latency
Chinese herbal medicine
X. strumarium
5′-long terminal repeat
nuclear regulatory proteins
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.720821/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.720821/full

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