Integrated multi-omics analysis of Alzheimer’s disease shows molecular signatures associated with disease progression and potential therapeutic targets
Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by the formation of amyloid plaques implicated in neuronal death. Genetics, age, and sex are the risk factors attributed to AD. Though omics studies have helped to identify pathways associated with AD, an inte...
Main Authors: | Pradeep Kodam, R. Sai Swaroop, Sai Sanwid Pradhan, Venketesh Sivaramakrishnan, Ramakrishna Vadrevu |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-03-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-30892-6 |
Similar Items
-
Integrated Transcriptome and Metabolomic Analysis Reveal Anti-Angiogenic Properties of Disarib, a Novel Bcl2-Specific Inhibitor
by: Meghana Manjunath, et al.
Published: (2022-07-01) -
Integrated multi-omics analysis of Huntington disease identifies pathways that modulate protein aggregation
by: Sai S. Pradhan, et al.
Published: (2022-10-01) -
Integrated Omic Analysis Delineates Pathways Modulating Toxic TDP-43 Protein Aggregates in Amyotrophic Lateral Sclerosis
by: Saiswaroop Rajaratnam, et al.
Published: (2023-04-01) -
CD9 role in proliferation, rejuvenation, and therapeutic applications
by: Sai Priyanka Kodam, et al.
Published: (2024-05-01) -
CardiOmics signatures reveal therapeutically actionable targets and drugs for cardiovascular diseases
by: María José Ramos-Medina, et al.
Published: (2024-01-01)