Falls in community-dwelling women with bipolar disorder: a case–control study
Abstract Background Falls are a common occurrence in psychiatric hospital settings, however population-based research among individuals with psychiatric disorders, in particular bipolar disorder (BD) is scant. Thus, we aimed to investigate falls risk in community-dwelling women diagnosed with BD. Me...
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| Format: | Article |
| Language: | English |
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BMC
2022-09-01
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| Series: | BMC Psychiatry |
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| Online Access: | https://doi.org/10.1186/s12888-022-04258-7 |
| _version_ | 1818016809510502400 |
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| author | Amanda L. Stuart Julie A. Pasco Michael Berk Shae E. Quirk Heli Koivumaa-Honkanen Risto Honkanen Mohammadreza Mohebbi Lana J. Williams |
| author_facet | Amanda L. Stuart Julie A. Pasco Michael Berk Shae E. Quirk Heli Koivumaa-Honkanen Risto Honkanen Mohammadreza Mohebbi Lana J. Williams |
| author_sort | Amanda L. Stuart |
| collection | DOAJ |
| description | Abstract Background Falls are a common occurrence in psychiatric hospital settings, however population-based research among individuals with psychiatric disorders, in particular bipolar disorder (BD) is scant. Thus, we aimed to investigate falls risk in community-dwelling women diagnosed with BD. Methods Women with BD (cases, n = 119) were recruited from health care settings located in southeast Victoria, Australia. Age-matched controls (n = 357, ratio 3:1) without BD were participants in the Geelong Osteoporosis Study drawn from the same geographical region. Lifetime history of BD was identified by semi-structured clinical interview (SCID-IV/NP). Previous 12-month falls data were obtained via questionnaire. Information on mobility, alcohol use, general health, medication use, blood pressure, body mass index, socioeconomic status and use of a walking aid was collected. Generalised Estimating Equations, binary and ordinal logistic regression were used to determine the odds ratio (OR) and 95% confidence interval (CI) for falls following adjustment for confounders. Results During the 12-month period, 34 (28.6%, median age 48.4 yr) cases and 70 (19.6%, median age 49.1 yr) controls reported one fall; 22 (18.5%) cases and 18 (5.0%) controls reported ≥ two falls (p < 0.001). Cases had 2.5-fold increased odds of at least one fall and 2.9-fold increased likelihood of increasing falls categories (0 vs. 1 vs. 2 +), compared to controls [adjOR 2.5, 95%CI (1.8, 3.4), adjOR OR 2.9, 95%CI (2.0, 4.1)]. Conclusion Risk of falls was greater among women with BD. Balance training could be a research and clinical focus for falls prevention programs among women with bipolar disorder to prevent the detrimental outcomes associated with falling. |
| first_indexed | 2024-04-14T07:18:31Z |
| format | Article |
| id | doaj.art-352b80231ebe4102a0bdf208dce54488 |
| institution | Directory Open Access Journal |
| issn | 1471-244X |
| language | English |
| last_indexed | 2024-04-14T07:18:31Z |
| publishDate | 2022-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Psychiatry |
| spelling | doaj.art-352b80231ebe4102a0bdf208dce544882022-12-22T02:06:14ZengBMCBMC Psychiatry1471-244X2022-09-012211610.1186/s12888-022-04258-7Falls in community-dwelling women with bipolar disorder: a case–control studyAmanda L. Stuart0Julie A. Pasco1Michael Berk2Shae E. Quirk3Heli Koivumaa-Honkanen4Risto Honkanen5Mohammadreza Mohebbi6Lana J. Williams7School of Medicine, IMPACT the Institute for Mental and Physical Health and Clinical Translation, Deakin University, Barwon HealthSchool of Medicine, IMPACT the Institute for Mental and Physical Health and Clinical Translation, Deakin University, Barwon HealthSchool of Medicine, IMPACT the Institute for Mental and Physical Health and Clinical Translation, Deakin University, Barwon HealthSchool of Medicine, IMPACT the Institute for Mental and Physical Health and Clinical Translation, Deakin University, Barwon HealthInstitute of Clinical Medicine/Psychiatry, University of Eastern FinlandInstitute of Clinical Medicine, Kuopio Musculoskeletal Research Unit (KMRU), University of Eastern FinlandFaculty of Health, Deakin UniversitySchool of Medicine, IMPACT the Institute for Mental and Physical Health and Clinical Translation, Deakin University, Barwon HealthAbstract Background Falls are a common occurrence in psychiatric hospital settings, however population-based research among individuals with psychiatric disorders, in particular bipolar disorder (BD) is scant. Thus, we aimed to investigate falls risk in community-dwelling women diagnosed with BD. Methods Women with BD (cases, n = 119) were recruited from health care settings located in southeast Victoria, Australia. Age-matched controls (n = 357, ratio 3:1) without BD were participants in the Geelong Osteoporosis Study drawn from the same geographical region. Lifetime history of BD was identified by semi-structured clinical interview (SCID-IV/NP). Previous 12-month falls data were obtained via questionnaire. Information on mobility, alcohol use, general health, medication use, blood pressure, body mass index, socioeconomic status and use of a walking aid was collected. Generalised Estimating Equations, binary and ordinal logistic regression were used to determine the odds ratio (OR) and 95% confidence interval (CI) for falls following adjustment for confounders. Results During the 12-month period, 34 (28.6%, median age 48.4 yr) cases and 70 (19.6%, median age 49.1 yr) controls reported one fall; 22 (18.5%) cases and 18 (5.0%) controls reported ≥ two falls (p < 0.001). Cases had 2.5-fold increased odds of at least one fall and 2.9-fold increased likelihood of increasing falls categories (0 vs. 1 vs. 2 +), compared to controls [adjOR 2.5, 95%CI (1.8, 3.4), adjOR OR 2.9, 95%CI (2.0, 4.1)]. Conclusion Risk of falls was greater among women with BD. Balance training could be a research and clinical focus for falls prevention programs among women with bipolar disorder to prevent the detrimental outcomes associated with falling.https://doi.org/10.1186/s12888-022-04258-7Bipolar disorderFallPsychotropic medicationCase–controlPsychiatryNeuroscience |
| spellingShingle | Amanda L. Stuart Julie A. Pasco Michael Berk Shae E. Quirk Heli Koivumaa-Honkanen Risto Honkanen Mohammadreza Mohebbi Lana J. Williams Falls in community-dwelling women with bipolar disorder: a case–control study BMC Psychiatry Bipolar disorder Fall Psychotropic medication Case–control Psychiatry Neuroscience |
| title | Falls in community-dwelling women with bipolar disorder: a case–control study |
| title_full | Falls in community-dwelling women with bipolar disorder: a case–control study |
| title_fullStr | Falls in community-dwelling women with bipolar disorder: a case–control study |
| title_full_unstemmed | Falls in community-dwelling women with bipolar disorder: a case–control study |
| title_short | Falls in community-dwelling women with bipolar disorder: a case–control study |
| title_sort | falls in community dwelling women with bipolar disorder a case control study |
| topic | Bipolar disorder Fall Psychotropic medication Case–control Psychiatry Neuroscience |
| url | https://doi.org/10.1186/s12888-022-04258-7 |
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