TDP-43-Mediated Toxicity in HEK293T Cells: A Fast and Reproducible Protocol To Be Employed in the Search of New Therapeutic Options against Amyotrophic Lateral Sclerosis
Cytoplasmic TDP-43 aggregates are a hallmark of amyotrophic lateral sclerosis (ALS). Today, only two drugs are available for ALS treatment, and their modest effect prompts researchers to search for new therapeutic options. TDP-43 represents one of the most promising targets for therapeutic intervent...
Main Authors: | Débora Lanznaster, Jérôme Bourgeais, Clement Bruno, Rudolf C. Hergesheimer, Rose-Anne Thepault, Patrick Vourc’h, Philippe Corcia, Christian R. Andres, Olivier Herault, Hélène Blasco |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-12-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/9/1/68 |
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